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紧急情况下的麻疹预防与控制

Measles prevention and control in emergency settings.

作者信息

Toole M J, Steketee R W, Waldman R J, Nieburg P

出版信息

Bull World Health Organ. 1989;67(4):381-8.

Abstract

Outbreaks of measles continue to be a common occurrence among refugee and famine-affected children in emergency relief camps. Extremely high measles-associated mortality rates have been reported from refugee camps--where undernutrition is common--in several countries over the past 10 years. Mortality from measles is, however, preventable, and immunization against the disease is a high priority in emergency relief programmes, second only in importance to the provision of adequate food rations. All children aged 6 months to 5 years should be immunized with measles vaccine as soon as they enter an organized camp or settlement. Should supplies of measles vaccine be inadequate, children in feeding centres, or those otherwise identified as undernourished, are the top priority for immunization. The occurrence of measles in a camp is not a contraindication to conducting an immunization campaign. Strong coordination by a designated lead agency is needed if such campaigns are to be successful; however, cooperation with the local expanded programme on immunization is essential to ensure that existing cold chain equipment, training protocols, and management manuals are used. If additional equipment is necessary, a complete immunization kit developed by the Office of the United Nations High Commissioner for Refugees, the World Health Organization, and Oxfam can be procured from Oxfam headquarters in the United Kingdom. Vitamin A supplements should be given routinely at the time of measles immunization in situations where malnutrition is severe. Mortality and morbidity in children with clinical measles can be reduced by administering high doses of vitamin A.

摘要

在紧急救援营地中,麻疹疫情在难民和受饥荒影响的儿童中持续常见。过去十年里,在几个国家的难民营(营养不良情况普遍)中,与麻疹相关的死亡率极高。然而,麻疹导致的死亡是可预防的,针对该疾病的免疫接种是紧急救援项目中的高度优先事项,在重要性上仅次于提供充足的口粮。所有6个月至5岁的儿童一旦进入有组织的营地或定居点,就应接种麻疹疫苗。如果麻疹疫苗供应不足,喂养中心的儿童或其他被确定为营养不良的儿童是免疫接种的首要对象。营地中出现麻疹并非开展免疫接种活动的禁忌证。要使此类活动取得成功,需要由指定的牵头机构进行有力协调;然而,与当地扩大免疫规划合作对于确保使用现有的冷链设备、培训方案和管理手册至关重要。如果需要额外设备,可以从乐施会英国总部采购由联合国难民事务高级专员公署、世界卫生组织和乐施会开发的完整免疫接种套件。在营养不良严重的情况下,应在麻疹免疫接种时常规给予维生素A补充剂。高剂量服用维生素A可降低患临床麻疹儿童的死亡率和发病率。

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