Khoury Madona, Stien Didier, Eparvier Véronique, Ouaini Naïm, El Beyrouthy Marc
CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 1 Avenue de la Terrasse, 91198 Gif-sur-Yvette, France; Department of Agricultural Sciences, Holy Spirit University of Kaslik, Kaslik, B.P. 446, Jounieh, Lebanon.
CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 1 Avenue de la Terrasse, 91198 Gif-sur-Yvette, France; Sorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes (LBBM), Observatoire Océanologique, 66650 Banyuls-sur-mer, France.
Evid Based Complement Alternat Med. 2016;2016:2547169. doi: 10.1155/2016/2547169. Epub 2016 Dec 8.
Many Lamiaceae species are consumed in the Lebanese cuisine as food or condiment and are largely used in the traditional medicine of Lebanon to treat various diseases, including microbial infections. In this article we report the traditional medicinal uses of eleven Lamiaceae species: L., L., Mill., L. subsp. , L., , Miller., Ten., L., L., and L. and study the chemical composition and antimicrobial activity of their essential oils (EOs). Our survey showed that Lamiaceae species are mainly used against gastrointestinal disorders and microbial infections. Chemical analysis of the EOs obtained from these plants allowed us to identify seventy-five compounds describing more than 90% of the relative composition of each EO. Essential oils with high amounts of thymol and carvacrol possessed the strongest antimicrobial activity. As expected, these two compounds demonstrated an interesting antifungal efficacy against the filamentous fungus . Our results confirmed that some of the Lamiaceae species used in Lebanon ethnopharmacological practices as antimicrobial agents do possess antibacterial and antifungal potential consistent with their use in alternative or complementary medicine.
许多唇形科植物在黎巴嫩菜肴中作为食物或调味品食用，并且在黎巴嫩传统医学中大量用于治疗包括微生物感染在内的各种疾病。在本文中，我们报告了11种唇形科植物的传统药用用途：[具体植物名称1]、[具体植物名称2]、[具体植物名称3]、[具体植物名称4]亚种[具体名称]、[具体植物名称5]、[具体植物名称6]、[具体植物名称7]、[具体植物名称8]、[具体植物名称9]、[具体植物名称10]和[具体植物名称11]，并研究了它们精油（EOs）的化学成分和抗菌活性。我们的调查表明，唇形科植物主要用于治疗胃肠道疾病和微生物感染。对从这些植物中获得的精油进行化学分析，使我们能够鉴定出75种化合物。这些化合物占每种精油相对组成的90%以上。含有大量百里香酚和香芹酚的精油具有最强的抗菌活性。不出所料，这两种化合物对丝状真菌[具体真菌名称]表现出有趣的抗真菌效果。我们的结果证实，黎巴嫩民族药理学实践中用作抗菌剂的一些唇形科植物确实具有抗菌和抗真菌潜力，这与它们在替代医学或补充医学中的用途一致。
