Vural Fisun, Ciftci Seval, Vural Birol
Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
Golcuk Necati Celik State Hospital, Kocaeli, Turkey.
North Clin Istanb. 2015 Jan 24;1(3):147-152. doi: 10.14744/nci.2014.41636. eCollection 2014.
With the use of any drug comes the possibility of unintended consequences which when harmful are referred to as adverse drug reactions (ADRs). The development of national pharmacovigilance systems is the responsibility of all health workers. The aim of this study was to investigate the knowledge of nurses about pharmacovigilance and attitudes about ADR and adverse event reporting.
This descriptive-cross sectional study was performed in 112 nurses working in a public hospital. The questionnaire was applied about pharmacovigilance and adverse drug reactions. The knowledge, attitudes and practices about adverse drug reactions were asked.
The 74.1% of the nurses definition of "severe adverse effect" of drug therapy. The ratio of participants who knew that ADRs are reported to contact person responsible from pharmacovigilance was 34.9%. Although 70.5% of nurses knew the necessity of ADR reporting, the 8% of the nurses knew Turkish Pharmacovigilance Center (TÜFAM). Only 8% of nurses reported ADRs in their professionality.
Although most of the participants knew the importance of ADR event reporting, event reporting was low. Thiese results showed that there is a lack of knowledge about pharmacovigilance. Futher studies with different settings and healthcare staff are needed to improve awareness about pharmacovigilance.
使用任何药物都可能产生意外后果，当这些后果有害时，就被称为药物不良反应（ADR）。国家药物警戒系统的发展是所有卫生工作者的责任。本研究的目的是调查护士对药物警戒的了解以及对药物不良反应和不良事件报告的态度。
本描述性横断面研究在一家公立医院工作的112名护士中进行。应用了关于药物警戒和药物不良反应的问卷。询问了关于药物不良反应的知识、态度和做法。
74.1%的护士对药物治疗的“严重不良反应”进行了定义。知道药物不良反应要向药物警戒负责人报告的参与者比例为34.9%。虽然70.5%的护士知道报告药物不良反应的必要性，但只有8%的护士知道土耳其药物警戒中心（TÜFAM）。只有8%的护士在其职业中报告过药物不良反应。
虽然大多数参与者知道报告药物不良反应事件的重要性，但事件报告率较低。这些结果表明，对药物警戒缺乏了解。需要对不同环境和医护人员进行进一步研究，以提高对药物警戒的认识。
