Nguyen Thuy-Nhien, Thu Pham N Huong, Hung Ngo Trong, Son Do Hung, Tien Nguyen Thanh, Van Dung Nguyen, Quang Huynh Hong, Seidlein Lorenz von, Cheah Phaik Yeong, Dondorp Arjen M, Day Nicholas P J, White Nicholas J, Hien Tran Tinh
Oxford University Clinical Research Unit, Wellcome Trust Major Oversea Programme, Ho Chi Minh City, Vietnam.
Binh Phuoc Malaria Prevent and Control Center, Binh Phuoc, Vietnam.
Malar J. 2017 Jan 6;16(1):17. doi: 10.1186/s12936-016-1662-2.
As part of a targeted malaria elimination project, mass drug administrations (MDAs) were conducted in Vietnam. The impact of MDAs on malaria transmission depends largely on the efficacy of the anti-malarial drug regimen, the malaria epidemiology in the site and the population coverage. To explore why some people participate in MDAs and others do not, a quantitative survey of the villagers' perceptions was undertaken in Vietnam.
In 2013/2014 MDAs were conducted in a village in Binh Phuoc province and a village in Ninh Thuan province. Within three months of the drug administration, 59 respondents in a village in Binh Phuoc and 79 respondents in a village in Ninh Thuan were randomly selected and interviewed.
Comprehension of the purpose of the intervention was of paramount importance for participation in the intervention. Respondents aware that the intervention aims to protect against malaria were significantly more likely to participate than respondents who were unaware of the MDA's purpose. Secondly, how and by whom villagers were informed was critical for participation. There was a strong association between sensitization by an informant such as a member of the local health team with participation in the intervention.
The study suggests several approaches to increase participation in mass drug administration campaigns. Training trustworthy informants to sensitize the study population is critical to maximize village participation in this setting. To achieve high coverage the entire community must understand and agree with the intervention.
作为一项有针对性的疟疾消除项目的一部分，越南开展了大规模药物管理（MDA）活动。MDA对疟疾传播的影响很大程度上取决于抗疟药物方案的疗效、当地的疟疾流行病学情况以及人群覆盖率。为了探究为何有些人参与MDA而有些人不参与，在越南对村民的看法进行了定量调查。
2013/2014年，在平阳省的一个村庄和宁顺省的一个村庄开展了MDA活动。在药物管理后的三个月内，随机选取了平阳省一个村庄的59名受访者和宁顺省一个村庄的79名受访者进行访谈。
对干预目的的理解对于参与干预至关重要。意识到干预旨在预防疟疾的受访者比未意识到MDA目的的受访者更有可能参与。其次，村民如何以及由谁告知对参与也很关键。当地卫生团队成员等告知者进行的宣传与参与干预之间存在密切关联。
该研究提出了几种提高大规模药物管理活动参与度的方法。培训值得信赖的告知者以提高研究人群的认识，对于在这种情况下最大限度地提高村庄参与度至关重要。为了实现高覆盖率，整个社区必须理解并同意该干预措施。
