Namdari Mehrdad, Eatemadi Ali, Soleimaninejad Maryam, Hammed Aiyelabegan T
Department of Cardiology, Lorestan University of Medical Sciences, Khoramabad, Iran.
Department of Medical Biotechnology, School of Medicine, Lorestan University of Medical Sciences, Khoramabad, Iran; Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran; Razi Herbal Medicine Research Center, Lorestan University of Medical Science, Khorramabad, Iran.
Biomed Pharmacother. 2017 Mar;87:321-331. doi: 10.1016/j.biopha.2016.12.099. Epub 2017 Jan 5.
Herbal medicines have been routinely employed all over the world dated back from the ancient time and have been identified by patients and physicians for their excellent therapeutic value as they have lower adverse effects when compared with the modern medicines. Phytotherapeutics requires a scientific technique to deliver the active herbal extract in a controlled manner to avoid repeated administration and increase patient compliance. This can be reached by fabricating a novel drug delivery systems (NDDS) for herbal components. NDDSs does not only decrease the repeated dose to overcome ineffectiveness, but also help to increase potency by decreasing toxicity and elevating drug bioavailability. Nano-sized DDS of herbal drugs have a potential application for improving the activity and countering the problems related to herbal medicines. Hence, application of nanocarriers as an NDDS in the traditional herbal medicine system is important to treat more chronic diseases like infectious endocarditis.
草药从古至今一直在世界各地被常规使用，并且因其卓越的治疗价值而得到患者和医生的认可，因为与现代药物相比，它们的副作用更低。植物疗法需要科学技术以可控方式递送活性草药提取物，以避免重复给药并提高患者依从性。这可以通过为草药成分制造新型药物递送系统（NDDS）来实现。NDDS不仅可以减少重复剂量以克服无效性，还可以通过降低毒性和提高药物生物利用度来增强药效。草药的纳米级药物递送系统在改善活性和应对与草药相关的问题方面具有潜在应用。因此，将纳米载体作为NDDS应用于传统草药医学系统对于治疗更多慢性疾病如感染性心内膜炎很重要。
