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一个利用啮齿动物模型理解和推进跨期选择研究的框架。

A framework for understanding and advancing intertemporal choice research using rodent models.

作者信息

Fobbs Wambura C, Mizumori Sheri J Y

机构信息

Neuroscience Program, University of Washington, Seattle, WA 98195, United States.

Neuroscience Program, University of Washington, Seattle, WA 98195, United States; Psychology Department, University of Washington, Seattle, WA 98195, United States.

出版信息

Neurobiol Learn Mem. 2017 Mar;139:89-97. doi: 10.1016/j.nlm.2017.01.004. Epub 2017 Jan 5.

Abstract

Intertemporal choices are common and consequential to private and public life. Thus, there is considerable interest in understanding the neural basis of intertemporal decision making. In this minireview, we briefly describe conceptual and psychological perspectives on intertemporal choice and then provide a comprehensive evaluation of the neural structures and signals that comprise the underlying cortico-limbic-striatal circuit. Even though great advances have been made, our understanding of the neurobiology of intertemporal choice is still in its infancy because of the complex and dynamic nature of this form of decision making. We close by briefly discussing recommendations for the future study of intertemporal choice research.

摘要

跨期选择很常见,对个人生活和公共生活都有重要影响。因此,人们对理解跨期决策的神经基础有着浓厚兴趣。在这篇迷你综述中,我们简要描述了跨期选择的概念和心理学观点,然后对构成潜在皮质-边缘-纹状体回路的神经结构和信号进行了全面评估。尽管已经取得了巨大进展,但由于这种决策形式的复杂性和动态性,我们对跨期选择神经生物学的理解仍处于起步阶段。最后,我们简要讨论了对跨期选择研究未来方向的建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ef3/5407470/4394961e7399/nihms843455f1.jpg

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