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自我控制的神经和机制基础。

On the Neural and Mechanistic Bases of Self-Control.

机构信息

Department of Psychology, The Ohio State University, Columbus, OH, USA.

Department of Psychology, Stanford University, Stanford, CA, USA.

出版信息

Cereb Cortex. 2019 Feb 1;29(2):732-750. doi: 10.1093/cercor/bhx355.

DOI:10.1093/cercor/bhx355
PMID:29373633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8921616/
Abstract

Intertemporal choice requires a dynamic interaction between valuation and deliberation processes. While evidence identifying candidate brain areas for each of these processes is well established, the precise mechanistic role carried out by each brain region is still debated. In this article, we present a computational model that clarifies the unique contribution of frontoparietal cortex regions to intertemporal decision making. The model we develop samples reward and delay information stochastically on a moment-by-moment basis. As preference for the choice alternatives evolves, dynamic inhibitory processes are executed by way of asymmetric lateral inhibition. We find that it is these lateral inhibition processes that best explain the contribution of frontoparietal regions to intertemporal decision making exhibited in our data.

摘要

跨期选择需要估值和审议过程之间的动态交互。虽然已经确定了每个过程的候选大脑区域的证据,但每个大脑区域执行的确切机制作用仍存在争议。在本文中,我们提出了一个计算模型,阐明了额顶叶皮层区域对跨期决策的独特贡献。我们开发的模型在逐点的基础上随机抽样奖励和延迟信息。随着对选择替代方案的偏好的发展,通过不对称的侧抑制来执行动态抑制过程。我们发现,正是这些侧抑制过程最好地解释了我们的数据中额顶叶区域对跨期决策的贡献。

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Approaches to Analysis in Model-based Cognitive Neuroscience.基于模型的认知神经科学中的分析方法。
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On the Functional Form of Temporal Discounting: An Optimized Adaptive Test.关于时间折扣的函数形式:一种优化的自适应测试。
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Factor analysis linking functions for simultaneously modeling neural and behavioral data.因子分析连接函数,用于同时对神经和行为数据进行建模。
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Why more is better: Simultaneous modeling of EEG, fMRI, and behavioral data.为何越多越好:脑电图(EEG)、功能磁共振成像(fMRI)及行为数据的同步建模
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Acute Stress Impairs Self-Control in Goal-Directed Choice by Altering Multiple Functional Connections within the Brain's Decision Circuits.急性应激通过改变大脑决策回路中的多个功能连接来损害目标导向选择中的自我控制。
Neuron. 2015 Aug 5;87(3):621-31. doi: 10.1016/j.neuron.2015.07.005.
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Eur J Neurosci. 2015 Sep;42(5):2179-89. doi: 10.1111/ejn.12997. Epub 2015 Aug 13.
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Money earlier or later? Simple heuristics explain intertemporal choices better than delay discounting does.早得钱还是晚得钱?简单启发式策略比延迟折扣更能解释跨期选择。
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