Mi Yu, Shao Zhiying, Vang Johnny, Kaidar-Person Orit, Wang Andrew Z
Laboratory of Nano- and Translational Medicine, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, Carolina Institute of Nanomedicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 USA ; Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 USA.
Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical College, Xuzhou, China.
Cancer Nanotechnol. 2016;7(1):11. doi: 10.1186/s12645-016-0024-7. Epub 2016 Dec 19.
Radiotherapy has been an integral treatment modality for cancer. The field arose from and progressed through innovations in physics, engineering, and biology. The evolution of radiation oncology will rely on the continued adoption of advances from other fields. A new area of science that possesses the ability to impact radiation oncology is nanomedicine. Materials on the nanoscale provide many unique properties such as enhanced permeability and retention effect and superparamagnetism that are well suited for applications in radiation oncology. In this review, we will provide a comprehensive summary on how nanotechnology can improve cancer radiotherapy in aspects of treatment delivery and monitoring as well as diagnosis.
放射治疗一直是癌症治疗的重要手段。该领域源于物理学、工程学和生物学的创新，并随着这些创新不断发展。放射肿瘤学的发展将依赖于持续采用其他领域的进展。一个有能力影响放射肿瘤学的新科学领域是纳米医学。纳米级材料具有许多独特的性质，如增强的渗透和滞留效应以及超顺磁性，非常适合应用于放射肿瘤学。在这篇综述中，我们将全面总结纳米技术如何在治疗实施、监测以及诊断等方面改善癌症放射治疗。
