Sarabia-Cobo Carmen M, Parás-Bravo Paula, Amo-Setién Francisco José, Alconero-Camarero Ana Rosa, Sáenz-Jalón María, Torres-Manrique Blanca, Sarabia-Lavín Raquel, Fernández-Rodríguez Angela, Silio-García Tamara, Fernández-Peña Rosario, Paz-Zulueta María, Santibáñez-Margüello Miguel
Department of Nursing, University of Cantabria, Cantabria, Spain.
PLoS One. 2017 Jan 9;12(1):e0169354. doi: 10.1371/journal.pone.0169354. eCollection 2017.
Measurement of health-related quality of life (HRQoL) is important for a chronic disease, such as dementia, which impairs the quality of life of affected patients in addition to their length of life. This is important in the context of economic evaluations when interventions do not (only) affect HRQoL and these other factors also affect overall quality of life.
To validate the Spanish translation of the ICECAP-O's capability to measure Health-related quality of life in elderly with dementia who live in nursing homes.
Cross-sectional study. For 217 residents living in 8 Spanish nursing homes, questionnaires were completed by nursing professionals serving as proxy respondents. We analyzed the internal consistency and other psychometric properties. We investigated the convergent validity of the ICECAP-O with other HRQoL instruments, the EQ-5D extended with a cognitive dimension (EQ-5D+C), the Alzheimer's Disease Related Quality of Life (ADRQL) measures, and the Barthel Index measure of activities of daily living (ADL).
The ICECAP-O presents satisfactory internal consistency (alpha 0.820). The factorial analysis indicated a structure of five principal dimensions that explain 66.57% of the total variance. Convergent validity between the ICECAP-O, EQ-5D+C, ADRQL, and Barthel Index scores was moderate to good (with correlations of 0.62, 0.61, and 0.68, respectively), but differed between dimensions of the instruments. Discriminant validity was confirmed by finding differences in ICECAP-O scores between subgroups based on ADL scores (0.70 low, 0.59 medium, and 0.39 high level care), dementia severity (0.72 mild, 0.63 medium, and 0.50 severe), and ages (0.59 below 75 years and 0.84 above 75 years).
This study presented the first use of a Spanish version of the ICECAP-O. The results indicate that the ICECAP-O appears to be a reliable Health-related quality of life measurement instrument showing good convergent and discriminant validity for people with dementia.
健康相关生活质量（HRQoL）的测量对于痴呆等慢性疾病很重要，这类疾病除了影响患者寿命外，还会损害其生活质量。在经济评估中，当干预措施并非（仅）影响HRQoL且其他因素也会影响总体生活质量时，这一点很重要。
验证ICECAP - O用于测量居住在养老院的老年痴呆患者健康相关生活质量的西班牙语翻译版本的有效性。
横断面研究。对于居住在8家西班牙养老院的217名居民，由护理专业人员作为代理应答者完成问卷。我们分析了内部一致性和其他心理测量特性。我们研究了ICECAP - O与其他HRQoL工具（扩展了认知维度的EQ - 5D（EQ - 5D + C）、阿尔茨海默病相关生活质量（ADRQL）测量工具以及日常生活活动（ADL）的巴氏指数测量工具）的收敛效度。
ICECAP - O具有令人满意的内部一致性（α = 0.820）。因子分析表明存在五个主要维度的结构，解释了总方差的66.57%。ICECAP - O、EQ - 5D + C、ADRQL和巴氏指数得分之间的收敛效度为中等至良好（相关性分别为0.62、0.61和0.68），但在工具的不同维度之间存在差异。基于ADL得分（低水平护理为0.70、中等水平护理为0.59、高水平护理为0.39）、痴呆严重程度（轻度为0.72、中度为0.63、重度为0.50）和年龄（75岁以下为0.59、75岁以上为0.84）的亚组间ICECAP - O得分差异证实了判别效度。
本研究首次使用了ICECAP - O的西班牙语版本。结果表明，ICECAP - O似乎是一种可靠的健康相关生活质量测量工具，对痴呆患者具有良好的收敛效度和判别效度。
