Persat Alexandre
School of Life Sciences, EPFL, Lausanne, Switzerland.
Curr Opin Microbiol. 2017 Apr;36:1-6. doi: 10.1016/j.mib.2016.12.002. Epub 2017 Jan 6.
Bacteria rapidly adapt to changes in their environment by leveraging sensing systems that permanently probe their surroundings. One common assumption is that such systems are responsive to signals that are chemical in nature. Yet, bacteria frequently experience changes in mechanical forces, for example as they transition from planktonic to sessile states. Do single bacteria actively sense and respond to mechanical forces? I here briefly review evidence indicating that bacteria actively respond to mechanical stimuli, and along concisely describe their intricate machinery enabling the transduction of force into biochemical activity.
细菌通过利用能够持续探测周围环境的传感系统迅速适应环境变化。一个常见的假设是，此类系统对本质上为化学性质的信号有反应。然而，细菌经常会经历机械力的变化，例如当它们从浮游状态转变为固着状态时。单个细菌会主动感知并对机械力做出反应吗？在此，我简要回顾表明细菌会主动对机械刺激做出反应的证据，并简要描述使其能够将力转化为生化活性的复杂机制。
