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德国的高血压

Hypertension in Germany.

作者信息

Neuhauser Hannelore, Diederichs Claudia, Boeing Heiner, Felix Stephan B, Jünger Claus, Lorbeer Roberto, Meisinger Christine, Peters Annette, Völzke Henry, Weikert Cornelia, Wild Philipp, Dörr Marcus

机构信息

Robert Koch Institute, Department 2: Epidemiology and Health Monitoring, Berlin; German Center for Cardiovascular Research (DZHK), Berlin Partner Site; German Institute of Human Nutrition (DIfE), Department of Epidemiology, Potsdam-Rehbrücke; Greifswald University Hospital, Department of Internal Medicine B; University Medical Center of the Johannes Gutenberg University Mainz, Preventive Cardiology and Medical Prevention; Institute of Clinical Radiology, Klinikum der Ludwig-Maximilians-Universität, München.

出版信息

Dtsch Arztebl Int. 2016 Dec 2;113(48):809-815. doi: 10.3238/arztebl.2016.0809.

Abstract

BACKGROUND

Hypertension is a key risk factor. However, population data based on blood pressure measurements in Germany are scarce.

METHODS

Standardized blood pressure (BP) measurements and medication data from seven population-based studies conducted in Germany between 1994 and 2012 (66 845 participants, 25-74 years) were analyzed: the EPICPotsdam study (1994-1998, EPIC), the KORA-S4 Study (1999-2001) in Augsburg, and the Gutenberg Health Study (2007-2012, GHS) in Mainz/Mainz-Bingen provided data for descriptive comparisons. Time trends were analyzed based on identical study regions for the German National Health Interview and Examination Survey 1998 (BGS98) and the German Health Examination Survey for Adults (2008-11, DEGS1) as well as the Study of Health in Pomerania (SHIP) in Northeast Germany (1997-2001) and the SHIP-TREND study (2008-2012). BP data were adjusted for study-specific measurement devices based on calibration studies.

RESULTS

After adjustment for study-specific measurement devices, mean systolic and diastolic BP values were lower and treatment proportions higher in recent (2007-2012) compared to older (1994-2001) studies. Mean BP decrease was most pronounced (systolic ≥ 10 mmHg) in the elderly (55-74 years). The regional SHIP-TREND data for Northeast Germany showed a decrease in mean systolic BP in young men aged 25 to 34 years; on a national level according to the DEGS1 data, however, no such decrease was observed for this group.

CONCLUSION

New data add evidence for lower BP in Germany. However, the prevention potential remains high. Future research based on population-based data should place a special focus on blood pressure data in young men.

摘要

背景

高血压是一个关键风险因素。然而,德国基于血压测量的人群数据稀缺。

方法

分析了1994年至2012年在德国进行的七项基于人群的研究中的标准化血压(BP)测量值和用药数据(66845名参与者,年龄在25 - 74岁之间):波茨坦欧洲癌症与营养前瞻性调查研究(1994 - 1998年,EPIC)、奥格斯堡的德国心血管研究中心S4研究(1999 - 2001年)以及美因茨/美因茨 - 宾根的古登堡健康研究(2007 - 2012年,GHS)提供了用于描述性比较的数据。基于相同研究区域,对1998年德国国民健康访谈与检查调查(BGS98)、德国成人健康检查调查(2008 - 2011年,DEGS1)以及德国东北部的波美拉尼亚健康研究(SHIP,1997 - 2001年)和SHIP - TREND研究(2008 - 2012年)的时间趋势进行了分析。根据校准研究,对BP数据针对特定研究的测量设备进行了调整。

结果

在针对特定研究的测量设备进行调整后,与较早(1994 - 2001年)的研究相比,近期(2007 - 2012年)研究中的平均收缩压和舒张压值更低,治疗比例更高。平均血压下降在老年人(55 - 74岁)中最为明显(收缩压≥10 mmHg)。德国东北部的SHIP - TREND区域数据显示,25至34岁年轻男性的平均收缩压有所下降;然而,根据DEGS1数据在全国范围内,该年龄组未观察到这种下降。

结论

新数据为德国较低的血压水平提供了证据。然而,预防潜力仍然很高。基于人群数据的未来研究应特别关注年轻男性的血压数据。

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