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2016年11月在韩国鸟类中分离出的新型高致病性禽流感(HPAI)H5N6病毒的基因特征分析

Genetic characterisation of novel, highly pathogenic avian influenza (HPAI) H5N6 viruses isolated in birds, South Korea, November 2016.

作者信息

Si Young-Jae, Lee In Won, Kim Eun-Ha, Kim Young-Il, Kwon Hyeok-Il, Park Su-Jin, Nguyen Hiep Dinh, Kim Se Mi, Kwon Jin-Jung, Choi Won-Suk, Beak Yun Hee, Song Min-Suk, Kim Chul-Joong, Webby Richard J, Choi Young-Ki

机构信息

College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.

These authors contributed equally to this work.

出版信息

Euro Surveill. 2017 Jan 5;22(1). doi: 10.2807/1560-7917.ES.2017.22.1.30434.

Abstract

A novel genotype of H5N6 influenza viruses was isolated from migratory birds in South Korea during November 2016. Domestic outbreaks of this virus were associated with die-offs of wild birds near reported poultry cases in Chungbuk province, central South Korea. Genetic analysis and animal studies demonstrated that the Korean H5N6 viruses are highly pathogenic avian influenza (HPAI) viruses and that these viruses are novel reassortants of at least three different subtypes (H5N6, H4N2 and H1N1).

摘要

2016年11月,韩国从候鸟中分离出一种新型H5N6流感病毒基因型。该病毒在韩国国内的爆发与韩国中部忠北省报告的家禽病例附近野生鸟类的死亡有关。基因分析和动物研究表明,韩国的H5N6病毒是高致病性禽流感(HPAI)病毒,并且这些病毒是至少三种不同亚型(H5N6、H4N2和H1N1)的新型重配体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/913c/5388099/3fab7d2d2baf/eurosurv-22-30434-f1.jpg

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