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The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health.人类肠道细菌 Christensenellaceae 分布广泛、可遗传，并与健康有关。
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本文引用的文献

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The composition of the gut microbiota throughout life, with an emphasis on early life.一生当中肠道微生物群的组成，重点关注生命早期。
Microb Ecol Health Dis. 2015 Feb 2;26:26050. doi: 10.3402/mehd.v26.26050. eCollection 2015.
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Human genetics shape the gut microbiome.人类遗传学塑造了肠道微生物组。
Cell. 2014 Nov 6;159(4):789-99. doi: 10.1016/j.cell.2014.09.053.
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Pfam: the protein families database.Pfam：蛋白质家族数据库。
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Gut metagenome in European women with normal, impaired and diabetic glucose control.肠道宏基因组与欧洲女性正常、受损和糖尿病患者的葡萄糖控制。
Nature. 2013 Jun 6;498(7452):99-103. doi: 10.1038/nature12198. Epub 2013 May 29.
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Gene Ontology annotations and resources.基因本体论注释和资源。
Nucleic Acids Res. 2013 Jan;41(Database issue):D530-5. doi: 10.1093/nar/gks1050. Epub 2012 Nov 17.
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A framework for human microbiome research.人类微生物组研究框架。
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Description of Christensenella minuta gen. nov., sp. nov., isolated from human faeces, which forms a distinct branch in the order Clostridiales, and proposal of Christensenellaceae fam. nov.Christensenella minuta gen. nov., sp. nov.，从人粪便中分离得到，属于梭菌目一个独特的分支，现提出 Christensenellaceae 科新名。
Int J Syst Evol Microbiol. 2012 Jan;62(Pt 1):144-149. doi: 10.1099/ijs.0.026989-0. Epub 2011 Feb 25.
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Interactions between gut microbiota and host metabolism predisposing to obesity and diabetes.肠道微生物群与宿主代谢之间的相互作用导致肥胖和糖尿病。
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PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes.PSORTb 3.0：通过改进定位亚类和提高对所有原核生物的预测能力，改善了蛋白质亚细胞定位预测。
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微小克里斯滕森菌DSM 22607T的基因组序列

Genome Sequence of Christensenella minuta DSM 22607T.

作者信息

Rosa Bruce A, Hallsworth-Pepin Kymberlie, Martin John, Wollam Aye, Mitreva Makedonka

机构信息

The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA.

The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA

出版信息

Genome Announc. 2017 Jan 12;5(2):e01451-16. doi: 10.1128/genomeA.01451-16.

DOI:10.1128/genomeA.01451-16
PMID:28082495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5256218/
Abstract

Obesity influences and is influenced by the human gut microbiome. Here, we present the genome of Christensenella minuta, a highly heritable bacterial species which has been found to be strongly associated with obesity through an unknown biological mechanism. This novel genome provides a valuable resource for future obesity therapeutic studies.

摘要

肥胖影响人类肠道微生物群，同时也受到其影响。在此，我们展示了微小克里斯滕森菌的基因组，这是一种具有高度遗传性的细菌物种，已发现它通过未知的生物学机制与肥胖密切相关。这个新的基因组为未来的肥胖治疗研究提供了宝贵的资源。