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两种植物发芽和未发芽种子提取物:生物化合物表征及体内外评价

Germinated and Ungerminated Seeds Extract from Two Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations.

作者信息

Andor Bogdan, Danciu Corina, Alexa Ersilia, Zupko Istvan, Hogea Elena, Cioca Andreea, Coricovac Dorina, Pinzaru Iulia, Pătrașcu Jenel Marian, Mioc Marius, Cristina Romeo Teodor, Soica Codruta, Dehelean Cristina

机构信息

Department of Orthopedics, University of Medicine and Pharmacy "Victor Babeş", Eftimie Murgu Square, No. 2, 300041 Timişoara, Romania.

Department of Pharmacognosy, University of Medicine and Pharmacy "Victor Babeş", Eftimie Murgu Square, No. 2, 300041 Timişoara, Romania.

出版信息

Evid Based Complement Alternat Med. 2016;2016:7638542. doi: 10.1155/2016/7638542. Epub 2016 Dec 20.

Abstract

In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of L. and L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests. Germination proved to be a method of choice in increasing the amount of genistein and cinnamic acid derivatives in both L. and seeds. Biological evaluation of all vegetal extracts revealed a weak therapeutic potential for both ungerminated and germinated seeds.

摘要

近年来,营养保健品因其作为预防各种健康问题的天然物质所做出的重大贡献,在生物医学研究中备受关注。对L.和L.未发芽及发芽种子的乙醇提取物进行了异黄酮(染料木黄酮)和肉桂酸衍生物含量分析。此外,还通过体外和体内试验对提取物的抗菌、抗增殖和抗炎特性进行了评估。事实证明,发芽是增加L.和种子中染料木黄酮和肉桂酸衍生物含量的一种优选方法。对所有植物提取物的生物学评估表明,未发芽和发芽种子的治疗潜力均较弱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/5206418/6a5b0e794885/ECAM2016-7638542.001.jpg

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