Matsuyoshi Saki, Murayama Ryosuke, Akiba Shunsuke, Yabuki Chiaki, Takamizawa Toshiki, Kurokawa Hiroyasu, Miyazaki Masashi
a Department of Operative Dentistry , Nihon University School of Dentistry , Chiyoda-ku , Tokyo , Japan.
Acta Odontol Scand. 2017 Apr;75(3):191-197. doi: 10.1080/00016357.2016.1277588. Epub 2017 Jan 16.
The purpose of this study was to examine the effects of a dentifrice containing 5% calcium sodium phosphosilicate (CSP) on the remineralization of the enamel using optical coherence tomography (OCT).
Bovine incisors were sliced and shaped in a rectangular form. One group of five specimens was treated with undersaturated 0.1 M lactic acid buffer solution (pH 4.75) for 10 min and then placed in artificial saliva (pH 7.0) (De group). Other specimens were stored in solutions of toothpaste containing CSP for 10 min, followed by 10-min immersion in the lactic acid buffer solution twice a day before storage in artificial saliva (CSP group). An additional group was stored in only artificial saliva (control group). OCT imaging on the selected location of the enamel surface was performed. The peak intensity and width at 1/e were recorded in each of the six areas on the sample and averaged, and the sample size of each group was six. The integrated value in units (dB × μm) was calculated in the area of peak intensity. The data for each group was subjected to one-way repeated-measures ANOVA and Tukey HSD tests (α = 0.05).
The changes in integrated values of each group were different. A slight but significant increase in the integrated value was observed in the control group, whereas a slight but significant decrease in the value was observed the De group. Integrated values increased in the CSP group.
Remineralization occurred upon immersion in the toothpaste containing CSP.
本研究旨在使用光学相干断层扫描（OCT）检查含5%磷酸硅钙钠（CSP）的牙膏对牙釉质再矿化的影响。
将牛切牙切成矩形并塑形。一组五个标本用不饱和0.1 M乳酸缓冲溶液（pH 4.75）处理10分钟，然后置于人工唾液（pH 7.0）中（脱矿组）。其他标本在含CSP的牙膏溶液中保存10分钟，然后每天两次在乳酸缓冲溶液中浸泡10分钟，之后再保存在人工唾液中（CSP组）。另一组仅保存在人工唾液中（对照组）。对牙釉质表面选定位置进行OCT成像。记录样品六个区域中每个区域的峰值强度和1/e处的宽度，并求平均值，每组样本量为六个。在峰值强度区域计算单位为（dB×μm）的积分值。对每组数据进行单向重复测量方差分析和Tukey HSD检验（α = 0.05）。
每组积分值的变化不同。对照组积分值有轻微但显著的增加，而脱矿组积分值有轻微但显著的下降。CSP组积分值增加。
浸泡在含CSP的牙膏中会发生再矿化。
