Nieto Javier, Uengoer Metin, Bernal-Gamboa Rodolfo
Facultad de Psicología, División de Investigación y Estudios de Posgrado, Universidad Nacional Autónoma de México, Coyoacán, 04510 Ciudad de México, Mexico.
Philipps-Universität Marburg, Marburg 35037, Germany.
Learn Mem. 2017 Jan 17;24(2):76-80. doi: 10.1101/lm.044495.116. Print 2017 Feb.
One experiment with rats explored whether an extinction-cue prevents the recovery of extinguished lever-pressing responses. Initially, rats were trained to perform one instrumental response (R1) for food in Context A, and a different instrumental response (R2) in Context B. Then, responses were extinguished each in the alternate context (R1 in Context B; R2 in Context A). For one group, extinction of both responses was conducted in the presence of an extinction-cue, whereas in a second group, the extinction-cue only accompanied extinction of R1. During a final test, we observed that returning the rats to the initial acquisition context renewed performance and that response recovery was attenuated in the presence of the cue that accompanied extinction of the response. The impact of the extinction-cue, however, was not transferred to the response that has been extinguished without the cue. Our results are consistent with the idea that extinction established an inhibitory cue-response association.
一项用大鼠进行的实验探究了消退线索是否会阻止已消退的杠杆按压反应的恢复。最初，大鼠在情境A中被训练为获取食物执行一种工具性反应（R1），在情境B中执行另一种不同的工具性反应（R2）。然后，在交替的情境中分别对反应进行消退（在情境B中消退R1；在情境A中消退R2）。对于一组，两种反应的消退都在消退线索存在的情况下进行，而在第二组中，消退线索仅伴随R1的消退。在最后的测试中，我们观察到将大鼠放回最初习得情境时行为表现得以恢复，并且在伴随反应消退的线索存在时反应恢复减弱。然而，消退线索的影响并未转移到在没有该线索情况下已消退的反应上。我们的结果与消退建立了抑制性线索 - 反应关联这一观点一致。
