Lorem Geir Fagerjord, Schirmer Henrik, Wang Catharina E A, Emaus Nina
Department of Health and Care Sciences, Faculty of Health Sciences, The Arctic University of Norway, Tromsø, Norway.
Department of Clinical Medicine, Faculty of Health Sciences, The Arctic University of Norway, Tromsø, Norway.
BMJ Open. 2017 Jan 18;7(1):e013629. doi: 10.1136/bmjopen-2016-013629.
It is known that self-reported health (SRH) declines with increasing age and that comorbidity increases with age. We wished to examine how age transfers its effect to SRH through comorbid disease and mental illness and whether these processes remained stable from 1994 until 2008. The hypothesis is that ageing and/or the increased age-related burden of pathology explains the declining SRH.
The Tromsø Study (TS) is a cohort study using a survey approach with repeated physical examinations. It was conducted in the municipality of Tromsø, Norway, from 1974 to 2008.
A total of 21 199 women and 19 229 men participated.
SRH is the outcome of interest. We calculated and compared the effect sizes of age, comorbidity and mental health symptoms using multimediator analysis based on OLS regression.
Ageing had a negative impact on SRH, but the total effect of age decreased from 1994 to 2007. We assessed the direct effect of age and then the proportion of indirect age-related effects through physical illness and mental health symptoms on the total effect. The direct effect of age represented 79.3% of the total effect in 1994 and decreased to 58.8% in 2007. Physical illness emerged as an increasingly important factor and increased its influence from 15.7% to 41.2% of the total effect. Age alone had a protective effect on mental health symptoms and this increased (2.5% to 17.3%), but we found a stronger association between mental health symptoms and physical disease in the later waves of the study (increasing from 3.7% to 14.8%).
The results suggest that the effect on SRH of mental health symptoms caused by physical illness is an increasing public health problem. Treatment and care for specific medical conditions must therefore focus more strongly on how these conditions affect the patient's mental health and address these concerns accordingly.
众所周知,自我报告的健康状况(SRH)会随着年龄增长而下降,且合并症也会随年龄增加。我们希望研究年龄如何通过合并疾病和精神疾病将其影响传递给SRH,以及从1994年到2008年这些过程是否保持稳定。假设是衰老和/或与年龄相关的病理负担增加解释了SRH的下降。
特罗姆瑟研究(TS)是一项队列研究,采用调查方法并进行重复体格检查。该研究于1974年至2008年在挪威特罗姆瑟市进行。
共有21199名女性和19229名男性参与。
SRH是感兴趣的结局。我们使用基于OLS回归的多中介分析计算并比较了年龄、合并症和心理健康症状的效应大小。
衰老对SRH有负面影响,但年龄的总效应从1994年到2007年有所下降。我们评估了年龄的直接效应,然后评估了通过身体疾病和心理健康症状产生的与年龄相关的间接效应在总效应中所占的比例。年龄的直接效应在1994年占总效应的79.3%,到2007年降至58.8%。身体疾病成为一个越来越重要的因素,其对总效应的影响从15.7%增加到41.2%。仅年龄对心理健康症状有保护作用,且这种作用有所增加(从2.5%增至17.3%),但我们发现在研究的后期阶段心理健康症状与身体疾病之间的关联更强(从3.7%增至14.8%)。
结果表明,身体疾病引起的心理健康症状对SRH的影响是一个日益严重的公共卫生问题。因此,针对特定医疗状况的治疗和护理必须更加强调这些状况如何影响患者的心理健康,并相应地解决这些问题。