Dale Nancy M, Myatt Mark, Prudhon Claudine, Briend André
1Tampere Centre for Child Health Research,University of Tampere and Tampere University Hospital,Lääkärinkatu 1,33014 University of Tampere,Finland.
2Brixton Health,Llawryglyn,UK.
Public Health Nutr. 2017 Jun;20(8):1362-1366. doi: 10.1017/S1368980016003578. Epub 2017 Jan 24.
When planning severe acute malnutrition (SAM) treatment services, estimates of the number of children requiring treatment are needed. Prevalence surveys, used with population estimates, can directly estimate the number of prevalent cases but not the number of subsequent incident cases. Health managers often use a prevalence-to-incidence conversion factor (J) derived from two African cohort studies to estimate incidence and add the expected number of incident cases to prevalent cases to estimate expected SAM caseload for a given period. The present study aimed to estimate J empirically in different contexts.
Observational study, with J estimated by correlating expected numbers of children to be treated, based on prevalence surveys, population estimates and assumed coverage, with the observed numbers of SAM patients treated.
Survey and programme data from six African and Asian countries.
Twenty-four data sets including prevalence surveys and programme admissions data for 5 months following the survey.
A statistically significant relationship between the number of SAM cases admitted to SAM treatment services and the estimated burden of SAM from prevalence surveys was found. Estimate for the slope (intercept forced to be zero) was 2·17 (95 % CI 1·33, 3·79). Estimates for the prevalence-to-incidence conversion factor J varied from 2·81 to 11·21, assuming programme coverage of 100 % and 38 %, respectively.
Estimation of expected caseload from prevalence may require revision of the currently used prevalence-to-incidence conversion factor J of 1·6. Appropriate values for J may vary between different locations.
在规划重度急性营养不良(SAM)治疗服务时,需要对需要治疗的儿童数量进行估计。患病率调查结合人口估计数可直接估算现患病例数,但无法估算后续新发病例数。卫生管理人员通常使用从两项非洲队列研究得出的患病率到发病率转换因子(J)来估算发病率,并将预期新发病例数与现患病例数相加,以估算给定时期内预期的SAM病例负担。本研究旨在根据不同情况对J进行实证估计。
观察性研究,通过将基于患病率调查、人口估计数和假定覆盖率得出的预期治疗儿童数与观察到的接受治疗的SAM患者数进行关联来估计J。
来自六个非洲和亚洲国家的调查和项目数据。
24个数据集,包括患病率调查和调查后5个月的项目入院数据。
发现进入SAM治疗服务的SAM病例数与患病率调查估计的SAM负担之间存在统计学显著关系。斜率估计值(截距强制为零)为2·17(95%可信区间1·33,3·79)。假设项目覆盖率分别为100%和38%,患病率到发病率转换因子J的估计值在2·81至11·21之间。
根据患病率估计预期病例负担可能需要修订目前使用的1·6的患病率到发病率转换因子J。J的适当值在不同地点可能有所不同。