Department of Materials Science & Engineering & IPPM-UTARI, University of Texas at Arlington, Arlington, TX 76019, USA.
Center for Nanomaterials and Sensor Development, State University of New York, Stony Brook, NY 11794, USA.
Sensors (Basel). 2017 Jan 20;17(1):199. doi: 10.3390/s17010199.
A common feature of the inflammatory response in patients who have actually contracted influenza is the generation of a number of volatile products of the alveolar and airway epithelium. These products include a number of volatile organic compounds (VOCs) and nitric oxide (NO). These may be used as biomarkers to detect the disease. A portable 3-sensor array microsystem-based tool that can potentially detect flu infection biomarkers is described here. Whether used in connection with in-vitro cell culture studies or as a single exhale breathalyzer, this device may be used to provide a rapid and non-invasive screening method for flu and other virus-based epidemics.
在实际上感染流感的患者的炎症反应中，一个共同的特征是肺泡和气道上皮产生许多挥发性产物。这些产物包括许多挥发性有机化合物(VOCs)和一氧化氮(NO)。这些可被用作检测疾病的生物标志物。这里描述了一种基于便携式 3 传感器阵列微系统的工具，它可以潜在地检测流感感染的生物标志物。无论是否与体外细胞培养研究结合使用，或者作为单个呼气式酒精检测仪，该设备都可用于提供流感和其他基于病毒的传染病的快速和非侵入性筛查方法。
