Basnet Syaron, Merikanto Ilona, Lahti Tuuli, Männistö Satu, Laatikainen Tiina, Vartiainen Erkki, Partonen Timo
Department of Health, National Institute for Health and Welfare, Helsinki, Finland; Faculty of Medicine, Department of Public Health, University of Helsinki, Helsinki, Finland.
Department of Health, National Institute for Health and Welfare, Helsinki, Finland; Department of Psychology, University of Helsinki, Helsinki, Finland.
Sleep Sci. 2016 Jul-Sep;9(3):249-254. doi: 10.1016/j.slsci.2016.11.003. Epub 2016 Nov 25.
A cross-sectional population-based survey, the National FINRISK 2012 Study, designed to monitor chronic diseases and their risk factors in Finland. A random sample of 10,000 adults aged 25-74 years, and of them, 64% (n=6424) participated the study. Participants subjectively reported the total durations for sleep and naps (n=6238), sleep quality (n=5878), bedtimes and wake-up times separately for working days and weekends yielding the amount of sleep debt (n=5878), and the seasonal variation in sleep duration (n=4852). The participants were asked whether they were diagnosed or treated for common chronic diseases in the past 12 months. Logistic regression models were adopted to analysis and adjusted for a range of covariates as potential confounding factors. Total sleep duration and nap duration prolonged in depression and other mental disorder (p<.001 for all). Seasonal variation in sleep duration was associated with depression (p=.014), hypertension (p=.018) and angina pectoris (p=.024). Participants with gallstones, cardiac insufficiency, depression, or degenerative arthritis had poor sleep quality (odds ratios of 1.6-6.3, p=.001 or less for each). Those with degenerative arthritis had sleep debt less (p<.05) and those with angina pectoris more (p<.05) than individuals without these medical conditions. Depression is significantly associated with sleep problems, albeit no sleep debt. Cardiovascular diseases, degenerative arthritis, and gallstones had significant associations with one or more sleep problems. There is therefore a need for more successful management of sleep problems in chronic diseases to improve the quality of life, to reduce treatment relapses, and to increase health and longevity in a population.
一项基于人群的横断面调查——2012年芬兰全国FINRISK研究,旨在监测芬兰的慢性病及其危险因素。随机抽取了10000名年龄在25至74岁之间的成年人,其中64%(n = 6424)参与了该研究。参与者主观报告了睡眠和小睡的总时长(n = 6238)、睡眠质量(n = 5878)、工作日和周末的就寝时间和起床时间,由此得出睡眠债的数量(n = 5878),以及睡眠时长的季节性变化(n = 4852)。参与者被问及在过去12个月内是否被诊断或治疗过常见慢性病。采用逻辑回归模型进行分析,并对一系列协变量作为潜在混杂因素进行了调整。抑郁症和其他精神障碍患者的总睡眠时长和小睡时长延长(所有p值均<0.001)。睡眠时长的季节性变化与抑郁症(p = 0.014)、高血压(p = 0.018)和心绞痛(p = 0.024)有关。患有胆结石、心脏功能不全、抑郁症或退行性关节炎的参与者睡眠质量较差(优势比为1.6 - 6.3每个p值均≤0.001)。与没有这些疾病的个体相比,患有退行性关节炎的人睡眠债较少(p < 0.05),而患有心绞痛的人睡眠债较多(p < 0.05)。抑郁症与睡眠问题显著相关,尽管没有睡眠债。心血管疾病、退行性关节炎和胆结石与一种或多种睡眠问题有显著关联。因此,有必要更成功地管理慢性病中的睡眠问题,以提高生活质量、减少治疗复发,并提高人群的健康水平和寿命。