Department of Pathology, Microbiology and Immunology, UC Davis School of Veterinary Medicine, 1044 Haring Hall, 1 Shields Avenue, Davis, CA, 95616, USA.
Department of Genetics and Microbiology, Faculty of Science, Charles University, Prague, Czech Republic.
Arch Virol. 2021 May;166(5):1521-1524. doi: 10.1007/s00705-021-05030-0. Epub 2021 Mar 15.
Polyomaviruses are ancient DNA viruses that infect several species of animals. While recognition of the family Polyomaviridae has grown rapidly, there are few studies that consider their potential association with disease. Carnivora are a diverse and widespread order affected by polyomaviruses (PyVs) that have co-evolved with their hosts for millions of years. PyVs have been identified in sea lions, raccoons, badgers, Weddell seals, and dogs. We have discovered a polyomavirus, tentatively named "Ursus americanus polyomavirus 1" (UaPyV1) in black bears (Ursus americanus). UaPyV1 was detectable in various tissues of six out of seven bears submitted for necropsy. Based on viral phylogenetic clustering and detection of the virus in multiple individuals, we suggest that black bears are the natural hosts for UaPyV1. In this albeit small group, there is no clear relationship between UaPyV1 infection and any specific disease.
多瘤病毒是一种古老的 DNA 病毒，可感染多种动物。虽然对多瘤病毒科的认识迅速增长，但很少有研究考虑它们与疾病的潜在关联。食肉目是一个多样化和广泛分布的目，受多瘤病毒（PyV）的影响，这些病毒与宿主共同进化了数百万年。已经在海狮、浣熊、獾、威德尔海豹和狗中发现了 PyV。我们在黑熊（Ursus americanus）中发现了一种多瘤病毒，暂命名为“美洲黑熊多瘤病毒 1”（UaPyV1）。在提交尸检的 7 只黑熊的各种组织中均可检测到 UaPyV1。基于病毒系统发育聚类和在多个个体中检测到该病毒，我们认为黑熊是 UaPyV1 的天然宿主。在这个规模虽然较小的群体中，UaPyV1 感染与任何特定疾病之间没有明确的关系。
