Yu Anthony F, Jones Lee W
Department of Medicine, Memorial Sloan Kettering Cancer Center, Cardiology Service, 1275 York Avenue, New York, NY, 10065, USA.
Cardiooncology. 2016;2:1. doi: 10.1186/s40959-016-0011-5. Epub 2016 Feb 25.
Advances in breast cancer treatment have improved disease-free survival and overall survival in women with early-stage breast cancer. However, these improvements may be attenuated by the adverse cardiovascular effects associated with breast cancer adjuvant therapy. Exercise may be a potential strategy to counteract these toxicities. The purpose of this paper is to provide an overview on the adverse cardiovascular effects of breast cancer therapy as well as the evidence supporting the potential cardioprotective effects of exercise training in breast cancer patients during and after treatment. We will also discuss research gaps and avenues for future research.
乳腺癌治疗的进展提高了早期乳腺癌女性的无病生存率和总生存率。然而，这些改善可能会因乳腺癌辅助治疗相关的不良心血管影响而减弱。运动可能是抵消这些毒性的潜在策略。本文的目的是概述乳腺癌治疗的不良心血管影响，以及支持运动训练在乳腺癌患者治疗期间和治疗后潜在心脏保护作用的证据。我们还将讨论研究空白和未来研究的方向。
