Zimmerman Allison, Planek Maria Isabel Camara, Chu Catherine, Oyenusi Opeyemi, Paner Agne, Reding Kerryn, Skeete Jamario, Clark Brian, Okwuosa Tochi M
Department of Medicine, Rush University Medical Center.
Rush Medical College, Rush University Medical Center.
Cardiovasc Endocrinol Metab. 2020 Sep 3;10(2):62-71. doi: 10.1097/XCE.0000000000000228. eCollection 2021 Jun.
Cardiovascular disease is one of the leading causes of morbidity and mortality in persons with cancer. The elevated risk is thought to derive from the combination of cardiovascular risk factors and direct cardiotoxicity from cancer therapies. Exercise may be a potential strategy to counteract these toxicities and maintain cardiovascular reserve. In this article, we review the evidence for the potential cardioprotective effects of exercise training in cancer patients before, during, and following treatment. We also propose a patient-tailored approach for the development of targeted prescriptions based on individual exercise capacity and cardiovascular reserve.
心血管疾病是癌症患者发病和死亡的主要原因之一。风险升高被认为源于心血管危险因素与癌症治疗直接导致的心脏毒性的综合作用。运动可能是抵消这些毒性并维持心血管储备的一种潜在策略。在本文中,我们回顾了运动训练在癌症患者治疗前、治疗期间和治疗后潜在心脏保护作用的证据。我们还提出了一种根据个体运动能力和心血管储备制定针对性处方的个性化方法。