Lau Nyok-Sean, Sam Ka-Kei, Amirul Abdullah Al-Ashraf
Centre for Chemical Biology, Universiti Sains Malaysia, Bayan Lepas, 11900 Penang Malaysia.
School of Biological Sciences, Universiti Sains Malaysia, Minden, 11800 Penang Malaysia.
Stand Genomic Sci. 2017 Jan 23;12:12. doi: 10.1186/s40793-017-0232-8. eCollection 2017.
sp. CCB-MM3 was one of several halophilic bacteria isolated from soil sediment in the estuarine Matang Mangrove, Malaysia. So far, no member from the genus , a member of the family, has been reported sequenced. In the current study, we present the first complete genome sequence of sp. strain CCB-MM3. The genome includes two chromosomes and five plasmids with a total length of 5,522,061 bp and an average GC content of 65%. Since a different strain of sp. (ND199) was reported to produce a polyhydroxyalkanoate copolymer, the ability for this production was tested and confirmed for strain CCB-MM3. Analysis of its genome sequence confirmed presence of a pathway for production of propionyl-CoA and gene cluster for PHA production in the sequenced strain. The genome sequence described will be a useful resource for understanding the physiology and metabolic potential of as well as for comparative genomic analysis with other .
CCB-MM3菌株是从马来西亚马当红树林河口的土壤沉积物中分离出的几种嗜盐细菌之一。到目前为止，尚未有该属（属于 科）的成员被报道进行过测序。在本研究中，我们展示了CCB-MM3菌株的首个完整基因组序列。该基因组包括两条染色体和五个质粒，总长度为5,522,061 bp，平均GC含量为65%。由于已报道不同菌株的 （ND199）可产生聚羟基脂肪酸酯共聚物，因此对CCB-MM3菌株进行了该生产能力的测试并得到证实。对其基因组序列的分析证实，在测序菌株中存在丙酰辅酶A的生产途径和PHA生产的基因簇。所描述的基因组序列将是了解 的生理学和代谢潜力以及与其他 进行比较基因组分析的有用资源。
