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科学家进行动物实验的目的是出于科学目的还是个人目的?

Why scientists perform animal experiments, scientific or personal aim?

作者信息

Mayir Burhan, Doğan Uğur, Bilecik Tuna, Yardımcı Erdem Can, Çakır Tuğrul, Aslaner Arif, Mayir Yeliz Akpınar, Oruç Mehmet Tahir

机构信息

Clinic of General Surgery, Antalya Training and Research Hospital, Antalya, Turkey.

出版信息

Ulus Cerrahi Derg. 2016 Oct 27;32(4):256-260. doi: 10.5152/UCD.2016.3196. eCollection 2016.

DOI:10.5152/UCD.2016.3196
PMID:28149122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5245717/
Abstract

OBJECTIVE

Although all animal studies are conducted in line with a specific purpose, we think that not all animal studies are performed for a scientific purpose but for personal curiosity or to fulfill a requirement. The aim of the present study is to reveal the purposes of experimental studies conducted on animals.

MATHERIAL AND METHODS

We searched for experimental studies performed on rats in general surgery clinics via PubMed, and obtained the e-mail addresses of the corresponding authors for each study. Afterwards, we sent a 7-item questionnaire to the authors and awaited their responses.

RESULTS

Seventy-three (22.2%) of 329 authors responded to the questionnaire. Within these studies, 31 (42.5%) were conducted as part of a dissertation, while the remaining 19 (26.0%) were conducted to meet the academic promotion criteria. Only 23 (31.5%) were conducted for scientific purposes. The cost of 41% of those studies was higher than 2500 $.

CONCLUSION

As shown in this study, the main objective of carrying out animal studies in Turkey is usually to prepare a dissertation or to be entitled to academic promotion. Animal experiments must be planned and performed as scientific studies to support related clinical studies. Additionally, animal studies must have well-defined objectives and be carried out in line with scientific purposes that may lead to useful developments in medicine, rather than personal interests.

摘要

目的

尽管所有动物研究都是按照特定目的进行的,但我们认为并非所有动物研究都是出于科学目的,而是出于个人好奇心或满足某种要求。本研究的目的是揭示在动物身上进行的实验研究的目的。

材料与方法

我们通过PubMed在普通外科诊所搜索了对大鼠进行的实验研究,并获取了每项研究通讯作者的电子邮件地址。之后,我们向作者发送了一份包含7个问题的问卷,并等待他们的回复。

结果

329名作者中有73名(22.2%)回复了问卷。在这些研究中,31项(42.5%)是作为论文的一部分进行的,其余19项(26.0%)是为了满足学术晋升标准而进行的。只有23项(31.5%)是出于科学目的进行的。其中41%的研究成本高于2500美元。

结论

如本研究所示,在土耳其进行动物研究的主要目的通常是撰写论文或获得学术晋升资格。动物实验必须作为科学研究来规划和实施,以支持相关的临床研究。此外,动物研究必须有明确的目标,并符合科学目的,从而可能在医学上带来有益的进展,而不是出于个人利益。

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Sociology. 2012 Aug;46(4):649-663. doi: 10.1177/0038038511435058.
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