Yuan Yi, Pang Na, Chen Yudong, Wang Yi, Li Xiaoli
Institute of Electrical Engineering, Yanshan University Qinhuangdao, China.
School of Control Engineering, Northeastern University at Qinhuangdao Qinhuangdao, China.
Front Comput Neurosci. 2017 Jan 20;11:1. doi: 10.3389/fncom.2017.00001. eCollection 2017.
Transcranial magneto-acoustical stimulation (TMAS) uses ultrasonic waves and a static magnetic field to generate electric current in nerve tissues for the purpose of modulating neuronal activities. It has the advantage of high spatial resolution and penetration depth. Neuronal firing rhythms carry and transmit nerve information in neural systems. In this study, we investigated the phase-locking characteristics of neuronal firing rhythms with TMAS based on the Hodgkin-Huxley neuron model. The simulation results indicate that the modulation frequency of ultrasound can affect the phase-locking behaviors. The results of this study may help us to explain the potential firing mechanism of TMAS.
经颅磁声刺激(TMAS)利用超声波和静磁场在神经组织中产生电流,以调节神经元活动。它具有高空间分辨率和穿透深度的优势。神经元放电节律在神经系统中携带和传递神经信息。在本研究中,我们基于霍奇金-赫胥黎神经元模型研究了经颅磁声刺激下神经元放电节律的锁相特性。模拟结果表明,超声调制频率会影响锁相行为。本研究结果可能有助于我们解释经颅磁声刺激的潜在放电机制。