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一项针对前列腺癌男性的临床医生转诊与12周运动训练计划:ENGAGE整群随机对照试验12个月的结果

A Clinician Referral and 12-Week Exercise Training Program for Men With Prostate Cancer: Outcomes to 12 Months of the ENGAGE Cluster Randomized Controlled Trial.

作者信息

Gaskin Cadeyrn J, Craike Melinda, Mohebbi Mohammadreza, Courneya Kerry S, Livingston Patricia M

出版信息

J Phys Act Health. 2017 May;14(5):353-359. doi: 10.1123/jpah.2016-0431. Epub 2017 Feb 7.

Abstract

BACKGROUND

The ENGAGE (efficacy of a referral and physical activity program for survivors of prostate cancer) study established that a clinician referral and 12-week exercise training program increased vigorous physical activity at 12 weeks among men with prostate cancer. Here, we report the 6- and 12-month outcomes.

METHODS

In this multicenter cluster randomized controlled trial, we compared a clinician referral and exercise training program to usual care. Discounted gym membership was offered to men in the intervention condition on completion of the 12-week exercise program. Self-reported physical activity at 6 and 12 months was the primary outcome. Quality of life, anxiety, and depressive symptoms were secondary outcomes.

RESULTS

A total of 147 men meeting eligibility criteria agreed to participate (54 intervention, 93 control). A positive interaction effect for vigorous physical activity was observed at 6 months, but not 12 months. No significant effects for the secondary outcomes were found.

CONCLUSIONS

A clinician referral and community-based supervised and unsupervised exercise training program, along with discounted gym membership, had a positive short-term effect on vigorous physical activity levels, but did not improve quality of life, in men with prostate cancer.

摘要

背景

ENGAGE(前列腺癌幸存者转诊与体育活动计划的疗效)研究表明,临床医生转诊和为期12周的运动训练计划可提高前列腺癌男性在12周时的剧烈身体活动水平。在此,我们报告6个月和12个月的结果。

方法

在这项多中心整群随机对照试验中,我们将临床医生转诊和运动训练计划与常规护理进行了比较。干预组的男性在完成12周运动计划后可享受打折的健身房会员资格。6个月和12个月时自我报告的身体活动情况为主要结局。生活质量、焦虑和抑郁症状为次要结局。

结果

共有147名符合资格标准的男性同意参与(54名干预组,93名对照组)。在6个月时观察到剧烈身体活动有积极的交互作用,但在12个月时未观察到。次要结局未发现显著影响。

结论

临床医生转诊以及基于社区的有监督和无监督运动训练计划,再加上打折的健身房会员资格,对前列腺癌男性的剧烈身体活动水平有积极的短期影响,但并未改善生活质量。

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