Reif J S, Wimmer L, Smith J A, Dargatz D A, Cheney J M
Department of Environmental Health, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
Am J Public Health. 1989 Nov;79(11):1528-30. doi: 10.2105/ajph.79.11.1528.
An outbreak of human cryptosporidiosis occurred among previously healthy persons in a veterinary medical teaching hospital. Human illness began after admission of calves from a farm which had been experiencing an epizootic of neonatal diarrhea due to Cryptosporidium. The clinical syndrome in humans was characterized by watery diarrhea, abdominal cramping, flatulence, and headache. Cryptosporidiosis was confirmed by zinc sulfate flotation of fecal specimens in four persons, three of whom had been responsible for the care and treatment of infected calves. A fourth patient had washed her husband's soiled clothing and appeared to have been infected indirectly through fomite contamination. Among 112 persons surveyed, 26 (23.2 percent) had a diarrheal illness during the outbreak and nine met the case definition of a diarrheal illness lasting at least three days. These persons were more likely to have had contact with a calf with diarrhea than were 52 referents who did not become ill during the outbreak.
一家兽医教学医院中,先前健康的人群中爆发了人类隐孢子虫病。在收治了来自一个农场的犊牛后,人类开始发病,该农场因隐孢子虫而暴发了新生犊牛腹泻 epizootic。人类的临床综合征表现为水样腹泻、腹部绞痛、肠胃胀气和头痛。通过对四名患者的粪便标本进行硫酸锌浮选,确诊为隐孢子虫病,其中三名患者负责照料和治疗受感染的犊牛。第四名患者清洗了其丈夫的脏衣服,似乎是通过污染物间接感染的。在接受调查的112人中,有26人(23.2%)在疫情暴发期间出现腹泻疾病,9人符合腹泻疾病持续至少三天的病例定义。与疫情暴发期间未患病的52名对照者相比,这些人更有可能接触过腹泻犊牛。