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使用拟合优度检验比较超弹性生存模型与其他单峰风险率函数。

Comparison of hypertabastic survival model with other unimodal hazard rate functions using a goodness-of-fit test.

作者信息

Tahir M Ramzan, Tran Quang X, Nikulin Mikhail S

机构信息

Department of Experimental Medicine, McGill University, Montreal, Canada.

Faculty of Foundation Studies, Thai Binh University, Vietnam.

出版信息

Stat Med. 2017 May 30;36(12):1936-1945. doi: 10.1002/sim.7244. Epub 2017 Feb 7.

Abstract

We studied the problem of testing a hypothesized distribution in survival regression models when the data is right censored and survival times are influenced by covariates. A modified chi-squared type test, known as Nikulin-Rao-Robson statistic, is applied for the comparison of accelerated failure time models. This statistic is used to test the goodness-of-fit for hypertabastic survival model and four other unimodal hazard rate functions. The results of simulation study showed that the hypertabastic distribution can be used as an alternative to log-logistic and log-normal distribution. In statistical modeling, because of its flexible shape of hazard functions, this distribution can also be used as a competitor of Birnbaum-Saunders and inverse Gaussian distributions. The results for the real data application are shown. Copyright © 2017 John Wiley & Sons, Ltd.

摘要

我们研究了在数据存在右删失且生存时间受协变量影响的情况下,生存回归模型中检验假设分布的问题。一种经过改进的卡方检验类型,即Nikulin-Rao-Robson统计量,被用于加速失效时间模型的比较。该统计量用于检验超巴斯分布生存模型及其他四种单峰风险率函数的拟合优度。模拟研究结果表明,超巴斯分布可作为对数逻辑分布和对数正态分布的替代。在统计建模中,由于其风险函数形状灵活,该分布也可作为Birnbaum-Saunders分布和逆高斯分布的竞争分布。文中展示了实际数据应用的结果。版权所有© 2017约翰·威利父子有限公司。

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