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编码人冠状病毒229E膜蛋白的基因的核苷酸序列。

Nucleotide sequence of the gene encoding the membrane protein of human coronavirus 229 E.

作者信息

Raabe T, Siddell S G

机构信息

Institute of Virology, University of Würzburg, Federal Republic of Germany.

出版信息

Arch Virol. 1989;107(3-4):323-8. doi: 10.1007/BF01317928.

DOI:10.1007/BF01317928
PMID:2818210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7086871/
Abstract

The sequence of the gene encoding the membrane protein of human coronavirus 229 E (HCV 229 E) has been determined. The primary translation product, deduced from the DNA sequence, is a polypeptide of 225 amino acids with a predicted molecular weight of 26,000. The polypeptide has 3 potential N-glycosylation sites. Many structural similarities with the membrane proteins of other coronaviruses can be recognized.

摘要

人类冠状病毒229E(HCV 229E)膜蛋白编码基因的序列已被确定。从DNA序列推导出来的初级翻译产物是一个由225个氨基酸组成的多肽,预测分子量为26,000。该多肽有3个潜在的N-糖基化位点。可以识别出它与其他冠状病毒的膜蛋白有许多结构相似性。

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本文引用的文献

1
Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing.DNA测序鸟枪法产生的凝胶读数数据的计算机处理自动化。
Nucleic Acids Res. 1982 Aug 11;10(15):4731-51. doi: 10.1093/nar/10.15.4731.
2
Clones of MRC-C cells may be superior to the parent line for the culture of 229E-like strains of human respiratory coronavirus.MRC-C细胞克隆在培养人呼吸道冠状病毒229E样毒株方面可能优于亲代细胞系。
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3
Characterization of viral proteins synthesized in 229E infected cells and effect(s) of inhibition of glycosylation and glycoprotein transport.在229E感染细胞中合成的病毒蛋白的特性以及糖基化抑制和糖蛋白转运的影响
Adv Exp Med Biol. 1984;173:65-77. doi: 10.1007/978-1-4615-9373-7_6.
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Epidemiology of coronavirus respiratory infections.冠状病毒呼吸道感染的流行病学
Arch Dis Child. 1983 Jul;58(7):500-3. doi: 10.1136/adc.58.7.500.
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A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.一对用于选择双酶切限制片段任一条DNA链的新型M13载体。
Gene. 1982 Oct;19(3):269-76. doi: 10.1016/0378-1119(82)90016-6.
7
A simple and very efficient method for generating cDNA libraries.一种简单且非常有效的生成cDNA文库的方法。
Gene. 1983 Nov;25(2-3):263-9. doi: 10.1016/0378-1119(83)90230-5.
8
The biology and pathogenesis of coronaviruses.冠状病毒的生物学特性与发病机制。
Curr Top Microbiol Immunol. 1982;99:165-200. doi: 10.1007/978-3-642-68528-6_5.
9
Polypeptides and functions of antigens from human coronaviruses 229E and OC43.人冠状病毒229E和OC43的多肽及抗原功能
Infect Immun. 1982 Feb;35(2):515-22. doi: 10.1128/iai.35.2.515-522.1982.
10
Coronavirus JHM: coding assignments of subgenomic mRNAs.冠状病毒JHM:亚基因组mRNA的编码分配
J Gen Virol. 1983 Jan;64 (Pt 1):113-25. doi: 10.1099/0022-1317-64-1-113.