• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

A feast for Candida: Metabolic plasticity confers an edge for virulence.

作者信息

Miramón Pedro, Lorenz Michael C

机构信息

Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center, Houston, Texas, United States of America.

出版信息

PLoS Pathog. 2017 Feb 9;13(2):e1006144. doi: 10.1371/journal.ppat.1006144. eCollection 2017 Feb.

DOI:10.1371/journal.ppat.1006144
PMID:28182769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5300112/
Abstract
摘要

相似文献

1
A feast for Candida: Metabolic plasticity confers an edge for virulence.念珠菌的盛宴：代谢可塑性赋予其致病优势。
PLoS Pathog. 2017 Feb 9;13(2):e1006144. doi: 10.1371/journal.ppat.1006144. eCollection 2017 Feb.
2
Synthesis of melanin pigment by Candida albicans in vitro and during infection.白色念珠菌在体外及感染过程中黑色素色素的合成。
Infect Immun. 2005 Sep;73(9):6147-50. doi: 10.1128/IAI.73.9.6147-6150.2005.
3
The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage.白色念珠菌菌丝形态发生与宿主细胞损伤之间的缺失环节
PLoS Pathog. 2016 Oct 20;12(10):e1005867. doi: 10.1371/journal.ppat.1005867. eCollection 2016 Oct.
4
Metabolic adaptation via regulated enzyme degradation in the pathogenic yeast Candida albicans.白色念珠菌致病酵母中通过调控酶降解实现的代谢适应。
J Mycol Med. 2017 Mar;27(1):98-108. doi: 10.1016/j.mycmed.2016.12.002. Epub 2016 Dec 29.
5
From commensal to pathogen: stage- and tissue-specific gene expression of Candida albicans.从共生菌到病原菌：白色念珠菌的阶段和组织特异性基因表达
Curr Opin Microbiol. 2004 Aug;7(4):336-41. doi: 10.1016/j.mib.2004.06.003.
6
Peroxisomal fatty acid beta-oxidation is not essential for virulence of Candida albicans.过氧化物酶体脂肪酸β氧化对于白色念珠菌的毒力并非必不可少。
Eukaryot Cell. 2006 Nov;5(11):1847-56. doi: 10.1128/EC.00093-06. Epub 2006 Sep 8.
7
Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence.白色念珠菌对一氧化氮的转录反应以及YHB1基因在亚硝化应激和毒力中的作用。
Mol Biol Cell. 2005 Oct;16(10):4814-26. doi: 10.1091/mbc.e05-05-0435. Epub 2005 Jul 19.
8
In situ mycotoxin production by Candida albicans in women with vaginitis.白色念珠菌在阴道炎女性患者中产生原位霉菌毒素的情况。
Gynecol Obstet Invest. 1995;39(1):67-9. doi: 10.1159/000292381.
9
The Absence of N-Acetyl-D-glucosamine Causes Attenuation of Virulence of Candida albicans upon Interaction with Vaginal Epithelial Cells In Vitro.N-乙酰-D-葡萄糖胺的缺失导致白色念珠菌在体外与阴道上皮细胞相互作用时毒力减弱。
Biomed Res Int. 2015;2015:398045. doi: 10.1155/2015/398045. Epub 2015 Aug 20.
10
Candida albicans gene expression in an in vivo infection model.白色念珠菌在体内感染模型中的基因表达。
Methods Mol Biol. 2009;499:77-83. doi: 10.1007/978-1-60327-151-6_9.

引用本文的文献

1
Wall incorporation of the β-1,3-glucan cross-linking protein Pir1 in the human pathogen Candida albicans is facilitated by the presence of two or more Pir repeat units.在人类病原体白色念珠菌中，两个或更多的Pir重复单元的存在促进了β-1,3-葡聚糖交联蛋白Pir1整合到细胞壁中。
FEMS Yeast Res. 2025 Jan 30;25. doi: 10.1093/femsyr/foaf042.
2
Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway.宿主白蛋白使白色念珠菌的代谢发生重定向，从而进入另一条致病途径。
Nat Commun. 2025 Jul 12;16(1):6447. doi: 10.1038/s41467-025-61701-5.
3
Fatty acid composition in the vaginal tract of cis-gender women: canary in coal mines for reproductive health?

本文引用的文献

1
Lactate signalling regulates fungal β-glucan masking and immune evasion.乳酸信号调节真菌β-葡聚糖的掩蔽和免疫逃避。
Nat Microbiol. 2016 Dec 12;2:16238. doi: 10.1038/nmicrobiol.2016.238.
2
Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids.白色念珠菌在羧酸中生长期间对细胞外pH的强大调节作用
mBio. 2016 Nov 15;7(6):e01646-16. doi: 10.1128/mBio.01646-16.
3
Candida parapsilosis Secreted Lipase as an Important Virulence Factor.近平滑念珠菌分泌脂肪酶作为一种重要的毒力因子。
顺性别女性阴道内的脂肪酸组成：生殖健康的煤矿中的金丝雀？
Lipids Health Dis. 2025 Mar 3;24(1):80. doi: 10.1186/s12944-025-02489-7.
4
Long-chain 4-aminoquinolines inhibit filamentation and increase efficacy of nystatin against Candida albicans infections in vivo.长链4-氨基喹啉可抑制丝状化，并增强制霉菌素对白色念珠菌体内感染的疗效。
NPJ Biofilms Microbiomes. 2024 Dec 13;10(1):146. doi: 10.1038/s41522-024-00608-3.
5
enhances virulence by progressive generation of new phenotypes.通过逐步产生新的表型增强毒力。
Curr Res Microb Sci. 2024 Nov 17;7:100316. doi: 10.1016/j.crmicr.2024.100316. eCollection 2024.
6
Candida albicans cells exhibit media specific proteomic profiles during induction of filamentation.白色念珠菌细胞在菌丝诱导过程中表现出特定于培养基的蛋白质组学特征。
BMC Microbiol. 2024 Nov 27;24(1):500. doi: 10.1186/s12866-024-03627-4.
7
Strain variation in glycolytic gene regulation.糖酵解基因调控中的应变变化。
mSphere. 2024 Nov 21;9(11):e0057924. doi: 10.1128/msphere.00579-24. Epub 2024 Oct 21.
8
Metabolic homeostasis in fungal infections from the perspective of pathogens, immune cells, and whole-body systems.真菌病感染中从病原体、免疫细胞和全身系统角度看代谢稳态
Microbiol Mol Biol Rev. 2024 Sep 26;88(3):e0017122. doi: 10.1128/mmbr.00171-22. Epub 2024 Sep 4.
9
Oral Mycobiota: A Narrative Review.口腔微生物群：一篇叙述性综述。
Dent J (Basel). 2024 Apr 19;12(4):115. doi: 10.3390/dj12040115.
10
Decoding the role of oxidative stress resistance and alternative carbon substrate assimilation in the mature biofilm growth mode of Candida glabrata.解析氧化应激抗性和替代碳源摄取在光滑念珠菌成熟生物膜生长模式中的作用。
BMC Microbiol. 2024 Apr 20;24(1):128. doi: 10.1186/s12866-024-03274-9.
Curr Protein Pept Sci. 2017;18(10):1043-1049. doi: 10.2174/1389203717666160813163054.
4
The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence.致病酵母中泛素化靶点的重新布线促进代谢灵活性、宿主定殖和毒力。
PLoS Pathog. 2016 Apr 13;12(4):e1005566. doi: 10.1371/journal.ppat.1005566. eCollection 2016 Apr.
5
The Candida albicans ATO Gene Family Promotes Neutralization of the Macrophage Phagolysosome.白色念珠菌 ATO 基因家族促进巨噬细胞吞噬体的中和作用。
Infect Immun. 2015 Nov;83(11):4416-26. doi: 10.1128/IAI.00984-15. Epub 2015 Sep 8.
6
Characterization of Virulence-Related Phenotypes in Candida Species of the CUG Clade.CUG进化枝念珠菌属中毒力相关表型的特征分析
Eukaryot Cell. 2015 Sep;14(9):931-40. doi: 10.1128/EC.00062-15. Epub 2015 Jul 6.
7
Transcriptomic analysis of vulvovaginal candidiasis identifies a role for the NLRP3 inflammasome.外阴阴道念珠菌病的转录组分析确定了NLRP3炎性小体的作用。
mBio. 2015 Apr 21;6(2):e00182-15. doi: 10.1128/mBio.00182-15.
8
Hyphal growth in Candida albicans does not require induction of hyphal-specific gene expression.白色念珠菌的菌丝生长并不需要诱导菌丝特异性基因表达。
Mol Biol Cell. 2015 Mar 15;26(6):1174-87. doi: 10.1091/mbc.E14-08-1312. Epub 2015 Jan 21.
9
Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels.新陈代谢在多个层面影响念珠菌的免疫原性和致病性。
Trends Microbiol. 2014 Nov;22(11):614-22. doi: 10.1016/j.tim.2014.07.001. Epub 2014 Jul 31.
10
The pathogen Candida albicans hijacks pyroptosis for escape from macrophages.病原体白色念珠菌劫持细胞焦亡从而逃避巨噬细胞的吞噬。
mBio. 2014 Mar 25;5(2):e00003-14. doi: 10.1128/mBio.00003-14.