Baukloh J K, Reeh M, Spinoglio G, Corratti A, Bartolini I, Mirasolo V M, Priora F, Izbicki J R, Gomez Fleitas M, Gomez Ruiz M, Perez D R
Department of General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf, Germany.
Department of General Surgery, Azienda University Hospital, Novara, Italy.
Eur J Surg Oncol. 2017 Jul;43(7):1304-1311. doi: 10.1016/j.ejso.2016.12.014. Epub 2017 Jan 19.
The feasibility and advantages of robotic rectal surgery (RRS) in comparison to conventional open or laparoscopic rectal resections have been postulated in several reports. But well-known challenges and pitfalls of minimal invasive rectal surgery have not been evaluated by a prospective, multicenter setting so far. Aim of this study was to analyze the perioperative outcome of patients following RRS especially in regard to the pitfalls such as obesity, male patients and low tumors by a European multicenter setting.
This prospective study included 348 patients undergoing robotic surgery due to rectal cancer in six major European centers. Clinicopathological parameters, morbidity, perioperative recovery and short-term outcome were analyzed.
A total of 283 restorative surgeries and 65 abdominoperineal resections were carried out. The conversion rate was 4.3%, mean blood loss was 191 ml, and mean operative time was 315 min. Postoperative complications with a Clavien-Dindo score >2 were observed in 13.5%. Obesity and low rectal tumors showed no significant higher rates of major complications or impaired oncological parameters. Male patients had significant higher rates of major complications and anastomotic leakage (p = 0.048 and p = 0.007, respectively).
RRS is a promising tool for improvement of rectal resections. The well-known pitfalls of minimal-invasive rectal surgery like obesity and low tumors were sufficiently managed by RRS. However, RRS showed significantly higher rates of major complications and anastomotic leakage in male patients, which has to be evaluated by future randomized trials.
多篇报道推测了机器人直肠手术(RRS)相较于传统开放或腹腔镜直肠切除术的可行性及优势。但迄今为止,微创直肠手术中一些众所周知的挑战和陷阱尚未在前瞻性多中心研究中得到评估。本研究的目的是通过欧洲多中心研究分析接受RRS患者的围手术期结果,尤其是针对肥胖、男性患者和低位肿瘤等陷阱方面。
这项前瞻性研究纳入了欧洲六个主要中心348例因直肠癌接受机器人手术的患者。分析了临床病理参数、发病率、围手术期恢复情况和短期结果。
共进行了283例保留性手术和65例腹会阴联合切除术。中转率为4.3%,平均失血量为191毫升,平均手术时间为315分钟。13.5%的患者出现Clavien-Dindo评分>2的术后并发症。肥胖和低位直肠肿瘤的主要并发症发生率或肿瘤学参数受损率均无显著升高。男性患者的主要并发症和吻合口漏发生率显著更高(分别为p = 0.048和p = 0.007)。
RRS是改善直肠切除术的一种有前景的工具。RRS能够充分应对微创直肠手术中诸如肥胖和低位肿瘤等常见陷阱。然而,RRS在男性患者中显示出显著更高的主要并发症和吻合口漏发生率,这有待未来的随机试验进行评估。