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改良完全无管经皮肾镜取石术:它是治疗肾及输尿管上段结石的有效且安全的选择吗?

Modified totally tubeless percutaneous nephrolithotomy: Is it an effective and safe treatment option for renal and upper ureteral stones?

作者信息

Chung Ho Seok, Jung Seung Il, Yu Ho Song, Hwang Eu Chang, Oh Kyung Jin, Kwon Dong Deuk, Park Kwangsung

机构信息

Department of Urology, Medical School, Chonnam National University, Gwangju, Korea.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2016;11(4):240-246. doi: 10.5114/wiitm.2016.64447. Epub 2016 Dec 6.

Abstract

INTRODUCTION

We hypothesized that modified totally tubeless percutaneous nephrolithotomy (PNL) without indwelling ureteral stent would minimize postoperative discomfort without complications.

AIM

To evaluate the safety, efficacy, and morbidity of standard, tubeless, and modified totally tubeless PNL as well as the usefulness of modified totally tubeless PNL.

MATERIAL AND METHODS

From November 2011 to February 2015, 211 patients who underwent PNL consecutively were enrolled in this study and divided into 3 groups (group 1: standard, group 2: tubeless, group 3: modified totally tubeless PNL). Patient and stone characteristics, operation time, hemoglobin change, length of hospitalization, stone-free rate, analgesic requirement, and perioperative complications were analyzed and compared among the 3 groups.

RESULTS

There were no significant differences in preoperative patient characteristics among the three groups. In the postoperative analysis, the three groups had similar operation time, stone-free rate, perioperative fever and transfusion rate, but group 2 showed superior results in terms of length of hospitalization (p = 0.001). Group 2 and group 3 had a lower analgesic requirement (p = 0.010). Immediate postoperative hemoglobin change (p = 0.001) and tube site complications (p = 0.001) were more common in group 1.

CONCLUSIONS

Modified totally tubeless PNL was not inferior in terms of postoperative outcomes and safety compared with the standard and tubeless PNL, and avoided the postoperative stent-related symptoms and cystoscopy for double-J stent removal. Modified totally tubeless PNL could be an alternative treatment of choice for management of renal or upper ureteral stones in selected patients.

摘要

引言

我们假设,不放置输尿管支架的改良完全无管经皮肾镜取石术(PNL)可将术后不适降至最低且无并发症。

目的

评估标准、无管及改良完全无管PNL的安全性、有效性和发病率,以及改良完全无管PNL的实用性。

材料与方法

2011年11月至2015年2月,连续接受PNL治疗的211例患者纳入本研究,分为3组(第1组:标准组,第2组:无管组,第3组:改良完全无管PNL组)。分析并比较3组患者的患者及结石特征、手术时间、血红蛋白变化、住院时间、结石清除率、镇痛需求及围手术期并发症。

结果

三组患者术前特征无显著差异。术后分析显示,三组手术时间、结石清除率、围手术期发热及输血率相似,但第2组在住院时间方面结果更佳(p = 0.001)。第2组和第3组镇痛需求较低(p = 0.010)。第1组术后即刻血红蛋白变化(p = 0.001)和造瘘口并发症(p = 0.001)更为常见。

结论

与标准及无管PNL相比,改良完全无管PNL在术后结果和安全性方面并不逊色,且避免了术后支架相关症状及拔除双J支架的膀胱镜检查。改良完全无管PNL可为部分选定患者的肾或上段输尿管结石治疗提供另一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399b/5299081/8db200c8e0f0/WIITM-11-28867-g001.jpg

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