Puri Poonam, Nandar Shashi Kumar, Kathuria Sushruta, Ramesh V
Department of Skin and STD, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, India.
Department of Environmental Toxicology Laboratory, National Institute of Pathology-ICMR, Safdarjung Hospital Campus, New Delhi, India.
Indian J Dermatol Venereol Leprol. 2017 Jul-Aug;83(4):415-423. doi: 10.4103/0378-6323.199579.
The increase in air pollution over the years has had major effects on the human skin. Various air pollutants such as ultraviolet radiation, polycyclic aromatic hydrocarbons, volatile organic compounds, oxides, particulate matter, ozone and cigarette smoke affect the skin as it is the outermost barrier. Air pollutants damage the skin by inducing oxidative stress. Although human skin acts as a biological shield against pro-oxidative chemicals and physical air pollutants, prolonged or repetitive exposure to high levels of these pollutants may have profound negative effects on the skin. Exposure to ultraviolet radiation has been associated with extrinsic skin aging and skin cancers. Cigarette smoke contributes to premature aging and an increase in the incidence of psoriasis, acne and skin cancers. It is also implicated in allergic skin conditions such as atopic dermatitis and eczema. Polyaromatic hydrocarbons are associated with extrinsic skin aging, pigmentation, cancers and acneiform eruptions. Volatile organic compounds have been associated with atopic dermatitis. Given the increasing levels of air pollution and its detrimental effects on the skin, it is advisable to use strategies to decrease air pollution.
多年来空气污染的加剧对人体皮肤产生了重大影响。各种空气污染物，如紫外线辐射、多环芳烃、挥发性有机化合物、氧化物、颗粒物、臭氧和香烟烟雾，都会对作为最外层屏障的皮肤产生影响。空气污染物通过诱导氧化应激来损害皮肤。虽然人体皮肤可作为抵御促氧化化学物质和物理性空气污染物的生物屏障，但长期或反复暴露于高水平的这些污染物可能会对皮肤产生深远的负面影响。紫外线辐射与皮肤外源性老化和皮肤癌有关。香烟烟雾会导致皮肤过早老化，并增加牛皮癣、痤疮和皮肤癌的发病率。它还与过敏性皮肤疾病如特应性皮炎和湿疹有关。多环芳烃与皮肤外源性老化、色素沉着、癌症和痤疮样皮疹有关。挥发性有机化合物与特应性皮炎有关。鉴于空气污染水平不断上升及其对皮肤的有害影响，建议采取减少空气污染的策略。
