肠道微生物群：对帕金森病的影响
Gut microbiota: Implications in Parkinson's disease.
作者信息
Parashar Arun, Udayabanu Malairaman
机构信息
Jaypee University of Information Technology, Waknaghat, District- Solan, Himachal Pradesh, PIN-173234, India.
Jaypee University of Information Technology, Waknaghat, District- Solan, Himachal Pradesh, PIN-173234, India.
出版信息
Parkinsonism Relat Disord. 2017 May;38:1-7. doi: 10.1016/j.parkreldis.2017.02.002. Epub 2017 Feb 7.
Abstract
Gut microbiota (GM) can influence various neurological outcomes, like cognition, learning, and memory. Commensal GM modulates brain development and behavior and has been implicated in several neurological disorders like Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, anxiety, stress and much more. A recent study has shown that Parkinson's disease patients suffer from GM dysbiosis, but whether it is a cause or an effect is yet to be understood. In this review, we try to connect the dots between GM and PD pathology using direct and indirect evidence.
摘要
肠道微生物群（GM）可影响多种神经学结果，如认知、学习和记忆。共生GM调节大脑发育和行为，并与多种神经疾病有关，如阿尔茨海默病、多发性硬化症、肌萎缩侧索硬化症、焦虑症、压力等等。最近的一项研究表明，帕金森病患者存在GM失调，但这是原因还是结果尚不清楚。在这篇综述中，我们试图利用直接和间接证据将GM与帕金森病病理学联系起来。
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