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一名儿科患者下颌骨的中央型毛细血管扩张性骨肉瘤:罕见病例

Central Telangiectatic Osteosarcoma of the Mandible in a Paediatric Patient: A Rarity.

作者信息

Tomar Divya, Dhillon Manu, Thayath Muhamad Nishad, Zaidi Iram, Singh Shikha

机构信息

Senior Lecturer, Department of Pedodontics and Preventive Dentistry, SBB Dental College and Research Centre , Ghaziabad, Uttar Pradesh, India .

Reader, Department of Oral Medicine and Radiology, ITS Centre for Dental Studies and Research , Ghaziabad, Uttar Pradesh, India .

出版信息

J Clin Diagn Res. 2016 Dec;10(12):XD01-XD03. doi: 10.7860/JCDR/2016/24038.9066. Epub 2016 Dec 1.

Abstract

Osteosarcoma (OS) involving the head and neck region is rare and is a diagnostic challenge due to its aggressive nature and varied presentations. Although OS constitute 40% to 60% of all bone tumours, only 10% of these occur in the head and neck region, most commonly in the maxilla and mandible. OS of the jaw bone has a different pattern and behaviour when compared to OS at other anatomic location. It occurs in a more elderly population, less aggressive and usually spreads locally rather than distant metastases. Telangiectatic Osteosarcoma (TOS) of jaws in a paediatric patient is still a very rare variant and till date only two cases have been reported in literature. Radiographic evaluation plays an important role as the clinical symptoms are not specific to the condition. Conventional radiography should always be supplemented by advanced imaging modalities for the diagnosis, which gives a three dimensional assessment and also prevents superimposition of surrounding structures. Early diagnosis and radical surgery are the keys to high survival rates. Herein, we present a third ever reported case of TOS occurring in mandible of a nine-year-old male patient.

摘要

头颈部骨肉瘤(OS)较为罕见,因其侵袭性和多样的表现形式而具有诊断挑战性。尽管骨肉瘤占所有骨肿瘤的40%至60%,但其中仅10%发生于头颈部区域,最常见于上颌骨和下颌骨。与其他解剖部位的骨肉瘤相比,颌骨骨肉瘤具有不同的模式和行为。它发生于年龄较大的人群,侵袭性较小,通常为局部扩散而非远处转移。小儿患者颌骨的毛细血管扩张性骨肉瘤(TOS)仍然是一种非常罕见的变异类型,迄今为止文献中仅报道过两例。由于临床症状对该病缺乏特异性,影像学评估起着重要作用。诊断时常规放射照相应始终辅以先进的成像方式,后者可进行三维评估并避免周围结构的重叠。早期诊断和根治性手术是高生存率的关键。在此,我们报告第三例发生于一名9岁男性患者下颌骨的毛细血管扩张性骨肉瘤。

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引用本文的文献

本文引用的文献

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Telangiectatic osteosarcoma affecting the mandible.发生于下颌骨的毛细血管扩张型骨肉瘤。
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