Simpson Jessica, Sallies Moegamat, Afrogheh Amir H
Department of Craniofacial Biology, Pathology & Radiology, Faculty of Dentistry, University of The Western Cape, Cape Town, South Africa.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of The Western Cape, Cape Town, South Africa.
Case Rep Dent. 2025 Apr 22;2025:7428891. doi: 10.1155/crid/7428891. eCollection 2025.
Osteosarcoma, the most common primary bone malignancy, rarely affects the jaw, representing only 6%-10% of cases. Jaw osteosarcoma typically occurs in individuals between the ages of 30 and 50 years and is uncommon in children. It often involves the mandible, especially in males, presenting with swelling, tooth mobility, and paraesthesia rather than pain. We present a rare case of jaw osteosarcoma in a 12-year-old girl who exhibited paraesthesia and a significant mandibular mass. Imaging demonstrated extensive mandibular involvement with Codman's triangle formation, and a biopsy confirmed the diagnosis of conventional osteosarcoma. The treatment approach included a hemimandibulectomy, followed by temporary reconstruction using a titanium plate and silastic spacer. This case underscores the importance of comprehensive evaluation and multidisciplinary management in diagnosing and treating osteosarcoma of the jaws in children. A review of 12 similar cases highlights the variability in presentation and treatment outcomes, emphasizing the need for individualized treatment plans to optimize patient prognosis.
骨肉瘤是最常见的原发性骨恶性肿瘤，很少累及颌骨，仅占病例的6%-10%。颌骨骨肉瘤通常发生在30至50岁的个体中，在儿童中并不常见。它常累及下颌骨，尤其是男性，表现为肿胀、牙齿松动和感觉异常而非疼痛。我们报告了一例罕见的12岁颌骨骨肉瘤女孩病例，她表现出感觉异常和明显的下颌肿物。影像学显示下颌骨广泛受累并形成科德曼三角，活检确诊为传统型骨肉瘤。治疗方法包括半侧下颌骨切除术，随后使用钛板和硅橡胶间隔物进行临时重建。该病例强调了在诊断和治疗儿童颌骨骨肉瘤时进行综合评估和多学科管理的重要性。对12例类似病例的回顾突出了临床表现和治疗结果的差异，强调需要制定个性化的治疗方案以优化患者预后。
