Lichtenstein M J, Burr M L, Fehily A M, Yarnell J W
Division of General Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 3732.
J Epidemiol Community Health. 1986 Dec;40(4):330-3. doi: 10.1136/jech.40.4.330.
Cross sectional data from a survey of 2512 men aged 45-49 years were used to examine the confounding effects of heart rate, employment, and ischaemic heart disease (IHD) on the relation between cereal fibre intake and blood pressure. Daily cereal fibre intake (g/day) was associated with systolic pressure (r = -0.053, p less than 0.01), diastolic pressure (r = -0.057, p less than 0.01), and heart rate (r = -0.071, p less than 0.01). The associations were strengthened in employed men and inapparent in unemployed men. Unemployed men had more IHD than employed men. Persons with any manifestation of IHD had significantly higher blood pressure and heart rates but ate less cereal fibre (7.0 v 7.9 g/day, p less than 0.001) than those without IHD, regardless of employment status. In employed men, after adjustment for age, body mass index, prevalent IHD, and heart rate, systolic pressure changed -0.186 mmHg (95% CI = -0.362, -0.009) and diastolic pressure changed -0.111 mmHg (95% CI = 0.228, 0.005) for each gram of cereal fibre eaten daily. The association between cereal fibre and blood pressure was inapparent in unemployed men. Heart rate, employment, and prevalent IHD confound the association between cereal fibre intake and blood pressure. Future work concerning this relationship will have to account for the effects of these variables.
对2512名年龄在45至49岁之间的男性进行调查所获得的横断面数据，用于研究心率、就业情况和缺血性心脏病（IHD）对谷物纤维摄入量与血压之间关系的混杂效应。每日谷物纤维摄入量（克/天）与收缩压（r = -0.053，p < 0.01）、舒张压（r = -0.057，p < 0.01）以及心率（r = -0.071，p < 0.01）相关。这些关联在就业男性中增强，而在失业男性中不明显。失业男性比就业男性患缺血性心脏病的更多。有任何缺血性心脏病表现的人，无论就业状况如何，其血压和心率显著更高，但摄入的谷物纤维比没有缺血性心脏病的人少（7.0对7.9克/天，p < 0.001）。在就业男性中，在调整年龄、体重指数、现患缺血性心脏病和心率后，每日每摄入1克谷物纤维，收缩压变化-0.186 mmHg（95%CI = -0.362，-0.009），舒张压变化-0.111 mmHg（95%CI = 0.228，0.005）。谷物纤维与血压之间的关联在失业男性中不明显。心率、就业情况和现患缺血性心脏病混淆了谷物纤维摄入量与血压之间的关联。关于这种关系的未来研究将必须考虑这些变量的影响。
