印度喜马偕尔邦西姆拉地区高海拔居住地儿童维生素D缺乏症患病率及相关风险因素
Prevalence of Vitamin D deficiency and associated risk factors among children residing at high altitude in Shimla district, Himachal Pradesh, India.
作者信息
Kapil Umesh, Pandey Ravindra Mohan, Goswami Ravinder, Sharma Brij, Sharma Neetu, Ramakrishnan Lakshmy, Singh Gajendra, Sareen Neha, Sati Hem Chandra, Gupta Aakriti, Sofi Nighat Yaseen
机构信息
Department of Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Indian J Endocrinol Metab. 2017 Jan-Feb;21(1):178-183. doi: 10.4103/2230-8210.196031.
INTRODUCTION
Vitamin D is important for bone development in children. A high prevalence of Vitamin D deficiency (VDD) has been documented from different parts of India. However, limited data are available on VDD among children residing at high altitude region of country.
OBJECTIVES
To assess the prevalence of VDD and associated risk factors among children in the age group of 6-18 years in Shimla, Himachal Pradesh.
METHODS
A community-based cross-sectional study was conducted in the year 2014-2015. A total of 626 children in the age group of 6-18 years were enrolled from 30 clusters which were identified using population proportionate to size sampling method. A minimum of 20 children in the age group of 6-18 years per cluster were selected using random number tables. The data on socioeconomic status, physical activity, sunlight exposure, and biochemical parameters of bone and mineral metabolism were assessed.
RESULTS
Ninety-three percent of school-age children were found Vitamin D deficient as per serum 25(OH) D levels of <20 ng/ml. The prevalence was significantly higher among females.
CONCLUSION
A high prevalence of VDD was found in children residing in high altitude region.
引言
维生素D对儿童骨骼发育至关重要。印度不同地区都有维生素D缺乏（VDD）高患病率的记录。然而，关于该国高海拔地区儿童VDD的数据有限。
目的
评估喜马偕尔邦西姆拉6至18岁儿童中VDD的患病率及相关危险因素。
方法
2014 - 2015年进行了一项基于社区的横断面研究。采用按规模大小成比例抽样方法从30个群组中选取了626名6至18岁的儿童。每个群组使用随机数字表选取至少20名6至18岁的儿童。评估了社会经济状况、身体活动、阳光照射以及骨和矿物质代谢的生化参数数据。
结果
根据血清25(OH)D水平<20 ng/ml，发现93%的学龄儿童维生素D缺乏。女性患病率显著更高。
结论
高海拔地区儿童中发现VDD患病率很高。
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