放疗对乳腺癌乳房切除术后患者心理、经济和性方面的影响：一项前瞻性研究与管理
Impact of Radiotherapy on Psychological, Financial, and Sexual Aspects in Postmastectomy Carcinoma Breast Patients: A Prospective Study and Management.
作者信息
Sharma Neelam, Purkayastha Abhishek
机构信息
Department of Radiation Oncology, Army Hospital Research and Referral, New Delhi, India.
出版信息
Asia Pac J Oncol Nurs. 2017 Jan-Mar;4(1):69-76. doi: 10.4103/2347-5625.199075.
OBJECTIVE
The aim of this study was to assess the impact of radiotherapy (RT) on psychological, financial, and sexual aspects in postmastectomy carcinoma breast patients affecting their quality of life (QOL) before, during, and after RT with a strong emphasis on their management and rehabilitation aspects.
METHODS
A cross-sectional study carried out in a specialized institution, comprising sixty women. Two standardized questionnaires European Organization for Research and Treatment of Cancer (EORTC) 30-item Quality of Life Questionnaire and Quality of Life Questionnaire breast cancer-23 (QLQ-BR23) for health-related quality, translated and validated for the Hindi language were used. The scores' manual of the EORTC was used to calculate the domain scores of the questionnaires.
RESULTS
According to the first questionnaire, the emotional function was most affected even at onset of RT treatment and it was worst at the completion of RT treatment with a mean score of 63.75. The global QOL score was also worst at the end of radiation treatment with a mean score of 32.36, while the score 3 months after completion of treatment was 68.16. The symptoms with the highest scores were insomnia with a worst scoring at completion of treatment (29.99), fatigue (26.57), and pain (23.05). According to the QLQ-BR23, the mean score for side effects such as sexual functioning was minimum 0.55 at the completion of RT, which improved to 11.66 on the first follow-up after 3 months. Mean future perspective score which was 57.22 before the start of RT which was reduced to 50.55 at completion, which means that many women experience side effects of RT and impaired sexual satisfaction.
CONCLUSIONS
Women with breast cancer showed changes in the following domains: financial, emotional, sexual satisfaction, and future prospects. The most frequently mentioned symptoms were fatigue, insomnia, and pain.
目的
本研究旨在评估放射治疗（RT）对乳腺癌乳房切除术后患者心理、经济和性方面的影响，这些方面会在放疗前、放疗期间和放疗后影响其生活质量（QOL），并特别强调对这些方面的管理和康复。
方法
在一家专业机构进行了一项横断面研究，研究对象为60名女性。使用了两份标准化问卷，即欧洲癌症研究与治疗组织（EORTC）的30项生活质量问卷和用于健康相关生活质量的乳腺癌-23生活质量问卷（QLQ-BR23），这两份问卷已翻译成印地语并经过验证。使用EORTC的评分手册计算问卷的领域得分。
结果
根据第一份问卷，即使在放疗开始时，情感功能受影响最大，在放疗结束时最差，平均得分为63.75。放疗结束时总体生活质量得分也最差，平均得分为32.36，而治疗完成后3个月的得分为68.16。得分最高的症状是失眠，在治疗结束时得分最高（29.99）、疲劳（26.57）和疼痛（23.05）。根据QLQ-BR23，放疗结束时性功能等副作用的平均得分最低为0.55，在3个月后的首次随访时提高到11.66。放疗开始前平均未来展望得分为57.22，放疗结束时降至50.55，这意味着许多女性经历了放疗的副作用和性满意度受损。
结论
乳腺癌女性在以下方面出现了变化：经济、情感、性满意度和未来前景。最常提到的症状是疲劳、失眠和疼痛。
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