Department of Urology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.
Department of Urology, Irumagawa Hospital, Gion 17-2, Sayama, Saitama, Japan.
World J Urol. 2017 Sep;35(9):1455-1461. doi: 10.1007/s00345-017-2014-8. Epub 2017 Feb 20.
To develop practical nomograms for predicting the stone-free rate after shock wave lithotripsy (SWL) in patients with a solitary stone in the proximal ureter.
Between July 2006 and June 2015, 319 patients with a proximal ureteral stone who underwent preoperative non-contrast enhanced computed tomography (NCCT) and subsequently received SWL were identified. Patients' age, gender, laterality, stone size, mean and maximum Hounsfield Unit (HU) of the stone, and skin-to-stone distance (SSD) were assessed. The stone-free status was defined as no radiopacity detected on the 3-month follow-up plain radiography or NCCT.
Mean stone size was 10 mm (range 3-20 mm). Mean and maximum HU of the stone ranged from 115 to 1447 (mean 701) and from 265 to 1881 (mean 1062), respectively. The overall stone-free rate was 70%. Multivariate analyses identified stone size (p < 0.001), maximum HU (p < 0.001), and SSD at 90° (p = 0.038) as independent predictive factors for the stone-free status after SWL. Nomograms could be constructed for predicting the probability of stone-free status after SWL corresponding to SSD of 8, 10, and 12 cm using maximum HU and stone size.
This study demonstrated that stone size, maximum HU of the stone, and SSD at 90° are significant predictors of successful SWL outcome in patients with a proximal ureteral stone. We have developed simple and practical nomograms corresponding to three different SSDs for predicting the stone-free rate after SWL.
为预测单独近端输尿管结石患者冲击波碎石(SWL)后无石率,建立实用的列线图。
2006 年 7 月至 2015 年 6 月,共 319 例接受术前非增强计算机断层扫描(NCCT)且随后接受 SWL 的近端输尿管结石患者。评估患者的年龄、性别、侧别、结石大小、结石的平均和最大亨氏单位(HU)值、以及皮肤至结石距离(SSD)。无石状态定义为 3 个月随访的平片或 NCCT 无放射密度。
平均结石大小为 10mm(范围 3-20mm)。结石的平均和最大 HU 值范围分别为 115-1447(均值 701)和 265-1881(均值 1062)。总的无石率为 70%。多变量分析确定结石大小(p<0.001)、最大 HU(p<0.001)和 90° SSD(p=0.038)是 SWL 后无石状态的独立预测因素。可以使用最大 HU 值和结石大小为 8、10 和 12cm 的 SSD 构建预测 SWL 后无石状态概率的列线图。
本研究表明,结石大小、结石的最大 HU 值和 90° SSD 是预测单独近端输尿管结石患者 SWL 结果的重要预测因素。我们已经开发了三种不同 SSD 对应的简单实用的列线图,用于预测 SWL 后的无石率。