Suppr超能文献

大猩猩β-珠蛋白基因簇中近期插入的一个Alu序列。

Recent insertion of an Alu sequence in the beta-globin gene cluster of the gorilla.

作者信息

Trabuchet G, Chebloune Y, Savatier P, Lachuer J, Faure C, Verdier G, Nigon V M

机构信息

Département de Biologie Générale et Appliquée Claude Bernard-Lyon, Villeurbanne, France.

出版信息

J Mol Evol. 1987;25(4):288-91. doi: 10.1007/BF02603112.

Abstract

We present the nucleotide sequence of a new Alu family member that lies between the delta- and beta-globin genes in gorilla DNA. The sequence exhibits 91% similarity with a consensus sequence of the Alu family. It is flanked by a perfect repetition of a 16-nucleotide target sequence and terminates with 24 adenylic residues. As this sequence is absent at this locus in other primate DNAs, its insertion occurred less than 8 million years ago, thus supporting the idea that Alu sequences are still mobile elements in the hominoid genome.

摘要

我们展示了一个新的Alu家族成员的核苷酸序列,它位于大猩猩DNA的δ-和β-珠蛋白基因之间。该序列与Alu家族的共有序列具有91%的相似性。它两侧是一个16个核苷酸靶序列的完美重复,并以24个腺苷酸残基结尾。由于该序列在其他灵长类动物DNA的这个位点不存在,其插入发生在不到800万年前,因此支持了Alu序列在类人猿基因组中仍然是可移动元件的观点。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验