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为什么我们的胃里还会有幽门螺旋杆菌?

Why do we still have Helicobacter Pylori in our Stomachs.

作者信息

Abadi Amin Talebi Bezmin, Ierardi Enzo, Lee Yeong Yeh

机构信息

Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, PO Box 14115-111, Tehran, Iran.

Division of Gastroenterology, Department of Emergency and Organ Transplantation, Piazza Giulio Cesare, 70124 Bari, Italy.

出版信息

Malays J Med Sci. 2015 Sep;22(5):70-75.

Abstract

The existence of any infectious agent in a highly acidic human stomach is contentious, but the chance finding of is by no means an accident. Once colonises the gastric mucosa, it can persist for a lifetime, and it is intriguing why our immune system is able to tolerate its existence. Some conditions favour the persistence of in the stomach, but other conditions oppose the colonisation of this bacterium. Populations with high and extremely low prevalence of provide useful insights on the clinical outcomes that are associated with this type of infection. Adverse clinical outcomes including peptic ulcer disease and gastric cancer depend on a delicate balance between a harmless inflammation and a more severe kind of inflammation. Is the only good really a dead ? The jury is still out.

摘要

在高度酸性的人类胃中存在任何感染因子都存在争议,但偶然发现[具体内容缺失]绝非偶然。一旦[具体内容缺失]定殖于胃黏膜,它就能终生持续存在,而令人好奇的是我们的免疫系统为何能够容忍其存在。有些条件有利于[具体内容缺失]在胃中持续存在,但其他条件则不利于这种细菌的定殖。[具体内容缺失]患病率高和极低的人群为与这类感染相关的临床结果提供了有用的见解。包括消化性溃疡病和胃癌在内的不良临床结果取决于无害炎症和更严重炎症之间的微妙平衡。[具体内容缺失]真的只有死了才是好的吗?尚无定论。

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