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通过一步滚环扩增产生的具有稳定催化能力的纯DNA水凝胶。

A pure DNA hydrogel with stable catalytic ability produced by one-step rolling circle amplification.

作者信息

Huang Yishun, Xu Wanlin, Liu Guoyuan, Tian Leilei

机构信息

Department of Materials Science and Engineering, Southern University of Science and Technology, 1088 Xueyuan Blvd., Xili, Nanshan District, Shenzhen, Guangdong 518055, China.

出版信息

Chem Commun (Camb). 2017 Mar 9;53(21):3038-3041. doi: 10.1039/c7cc00636e.

Abstract

A rolling-circle-amplification method was developed to produce DNA hydrogels with horseradish-peroxidase-like catalytic capability. The catalytic hydrogel exhibits highly improved stability at elevated temperatures or during a long-term storage. Integrated with glucose oxidase, the complex hydrogel can be applied to the sensitive and reliable detection of glucose.

摘要

开发了一种滚环扩增方法来制备具有辣根过氧化物酶样催化能力的DNA水凝胶。这种催化水凝胶在高温或长期储存过程中表现出显著提高的稳定性。与葡萄糖氧化酶结合,这种复合水凝胶可用于灵敏可靠地检测葡萄糖。

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