人T细胞白血病病毒I型的pX产物对猿猴病毒40增强子的反式激活作用
trans-activation of the simian virus 40 enhancer by a pX product of human T-cell leukemia virus type I.
作者信息
Saito S, Nakamura M, Ohtani K, Ichijo M, Sugamura K, Hinuma Y
机构信息
Institute for Virus Research, Kyoto University, Japan.
出版信息
J Virol. 1988 Feb;62(2):644-8. doi: 10.1128/JVI.62.2.644-648.1988.
Abstract
A trans-acting factor, p40, of human T-cell leukemia virus type I profoundly potentiated the function of the enhancer from simian virus 40 but not polyomavirus and Rous sarcoma and murine sarcoma viruses. This trans-activation was seen in a limited repertoire of cells, in contrast to trans-activation of the human T-cell leukemia virus type I enhancer by p40.
摘要
人I型T细胞白血病病毒的一种反式作用因子p40能显著增强猿猴病毒40增强子的功能，但对多瘤病毒、劳氏肉瘤病毒和鼠肉瘤病毒的增强子则无此作用。与p40对人I型T细胞白血病病毒增强子的反式激活作用不同，这种反式激活作用仅在有限种类的细胞中可见。
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