Gong Ying-Ying, Zhang Fan, Zhou Jin, Li Jing, Zhang Guang-Hui, Wang Jun-Liang, Gu Zhen-Sheng
a Department of Ophthalmology, Xinhua Hospital , Shanghai Jiaotong University School of Medicine , Shanghai , China.
b Department of Ophthalmology , The Second People's Hospital of Kashi , Xinjiang , China.
Ophthalmic Epidemiol. 2017 Jun;24(3):181-187. doi: 10.1080/09286586.2016.1263996. Epub 2017 Feb 25.
To describe and compare the prevalence and characteristics of dry eye among Han and Uyghur persons living in Kashi, the most inland city of China.
A total of 1015 residents of Kashi participated in this 2013 cross-sectional study. To evaluate clinical characteristics, each subject completed (1) a dry-eye questionnaire detailing symptoms of dry eye, (2) Schirmer's I-test (SIT), (3) tear-film break-up time (BUT) test, and fluorescein staining of the cornea. Dry eye was defined as the existence of dry eye symptoms and at least two positive clinical signs. Data were analyzed using SPSS software. The prevalence and risk factors of dry eye were evaluated using a multivariate model.
Overall, 282 (27.8%) of the 1015 participants were diagnosed with dry eye (95% confidence interval (CI): range, 25.5-30.1). The prevalence of dry eye among Han persons (37.9 %) (95% CI: range, 35.8-40.0) was higher than that among Uyghurs (21.8%) (95% CI: 19.6-24.0) (p < 0.05). The prevalence of dry eye was 25.6% (95% CI: range, 23.3-27.8) among men and 28.7% (95% CI: 26.5-30.9) among women (p > 0.05). Risk factors for dry eye included ethnicity, age, occupation, arthritis, and dry mouth.
Our study revealed a higher prevalence of dry eye among Han than Uyghur persons in Kashi. Dry eye was significantly associated with environment and ethnicity.
描述并比较生活在中国最内陆城市喀什的汉族和维吾尔族人群中干眼的患病率及特征。
2013年共有1015名喀什居民参与了这项横断面研究。为评估临床特征，每位受试者完成了：（1）一份详细列出干眼症状的干眼问卷；（2）泪液分泌试验（SIT）；（3）泪膜破裂时间（BUT）试验以及角膜荧光素染色。干眼定义为存在干眼症状且至少有两项阳性临床体征。使用SPSS软件对数据进行分析。采用多变量模型评估干眼的患病率及危险因素。
总体而言，1015名参与者中有282人（27.8%）被诊断为干眼（95%置信区间（CI）：范围为25.5 - 30.1）。汉族人群中干眼的患病率（37.9%）（95% CI：范围为35.8 - 40.0）高于维吾尔族（21.8%）（95% CI：19.6 - 24.0）（p < 0.05）。男性干眼患病率为25.6%（95% CI：范围为23.3 - 27.8），女性为28.7%（95% CI：26.5 - 30.9）（p > 0.05）。干眼的危险因素包括种族、年龄、职业、关节炎和口干。
我们的研究显示，喀什汉族人群中干眼的患病率高于维吾尔族人群。干眼与环境和种族显著相关。
