Hu Jing-Wen, Zhu Xiu-Ping, Pan Shi-Yin, Yang Hua, Xiao Xiang-Hua
Department of Cardiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.
Shaanxi Institute of Ophthalmology, Xi'an City First Hospital, Xi'an 710002, Shaanxi Province, China.
Int J Ophthalmol. 2021 Apr 18;14(4):567-573. doi: 10.18240/ijo.2021.04.14. eCollection 2021.
To estimate the prevalence of and risk factors for dry eye disease (DED) in young and middle-aged office employee in Xi'an.
This cross-sectional study of the prevalence of and risk factors for DED investigated 486 young and middle-aged Chinese office employee in Xi'an. DED symptoms and potential risk factors were assessed using the ocular surface disease index combined with a risk factors questionnaire, and tear function was evaluated using the tear film break-up time and Schirmer's test. Possible risk factors for DED were estimated by binary Logistic regression analysis.
DED was diagnosed in 100 females and 96 males, giving a prevalence of 40.3% [95% confidence interval (CI)=36.0%-44.7%]. The multivariate binary Logistic regression model indicated that the possible risk factors for DED were being female (OR=1.592, 95%CI=1.034-2.451, =0.035), being aged ≥40y (OR=1.593, 95%CI=1.034-2.454, =0.035), using a VDT daily for >6h (OR=1.990, 95%CI=1.334-2.971, =0.001), the presence of central air conditioning (OR=1.548, 95%CI=1.053-2.276, =0.026), and self-reported dryness of the mouth and nose (OR=1.589, 95%CI=1.071-2.357, =0.021).
There is a high prevalence of clinically diagnosed DED in young and middle-aged video display terminal (VDT) users. Interventions against the modifiable risk factors should be taken to prevent the occurrence and development of DED in this population.
评估西安中青年办公室职员干眼疾病（DED）的患病率及危险因素。
这项关于DED患病率及危险因素的横断面研究调查了486名西安的中青年中国办公室职员。使用眼表疾病指数结合危险因素问卷评估DED症状和潜在危险因素，并使用泪膜破裂时间和泪液分泌试验评估泪液功能。通过二元Logistic回归分析估计DED的可能危险因素。
诊断出100名女性和96名男性患有DED，患病率为40.3%[95%置信区间（CI）=36.0%-44.7%]。多变量二元Logistic回归模型表明，DED的可能危险因素为女性（OR=1.592，95%CI=1.034-2.451，P=0.035）、年龄≥40岁（OR=1.593，95%CI=1.034-2.454，P=0.035）、每天使用视频终端（VDT）超过6小时（OR=1.990，95%CI=1.334-2.971，P=0.001）、有中央空调（OR=1.548，95%CI=1.053-2.276，P=0.026）以及自我报告的口鼻干燥（OR=1.589，95%CI=1.071-2.357，P=0.021）。
中青年视频显示终端（VDT）使用者中临床诊断DED的患病率较高。应针对可改变的危险因素采取干预措施，以预防该人群中DED的发生和发展。
