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布拉酵母菌益生菌治疗后发生的与导管相关的酿酒酵母菌菌血症:一名重症监护病房儿童病例及文献综述

Catheter-related Saccharomyces cerevisiae Fungemia Following Saccharomyces boulardii Probiotic Treatment: In a child in intensive care unit and review of the literature.

作者信息

Atıcı Serkan, Soysal Ahmet, Karadeniz Cerit Kıvılcım, Yılmaz Şerife, Aksu Burak, Kıyan Gürsu, Bakır Mustafa

机构信息

Department of Pediatrics and Division of Pediatric Infectious Diseases, Medical School, Marmara University, Istanbul, Turkey.

Department of Pediatric Surgery, Medical School, Marmara University, Istanbul, Turkey.

出版信息

Med Mycol Case Rep. 2017 Feb 22;15:33-35. doi: 10.1016/j.mmcr.2017.02.002. eCollection 2017 Mar.

Abstract

Although is usually a non-pathogenic fungus, in rare occasions it can cause invasive infection in children. We present the case of an 8-year-old patient in pediatric surgical intensive care unit who developed fungemia following probiotic treatment containing . Caspofungin was not effective in this case and he was treated with amphotericin B. We want to emphasize that physicians should be careful about probiotic usage in critically ill patients.

摘要

虽然通常是一种非致病性真菌,但在极少数情况下,它可导致儿童发生侵袭性感染。我们报告一例8岁患儿的病例,该患儿在儿科外科重症监护病房接受含有的益生菌治疗后发生了真菌血症。在该病例中,卡泊芬净无效,他接受了两性霉素B治疗。我们想强调的是,医生在危重症患者使用益生菌时应谨慎。

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本文引用的文献

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Review article: yeast as probiotics -- Saccharomyces boulardii.综述文章:作为益生菌的酵母——布拉氏酵母菌。
Aliment Pharmacol Ther. 2007 Sep 15;26(6):767-78. doi: 10.1111/j.1365-2036.2007.03442.x.
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Saccharomyces cerevisiae fungemia: an emerging infectious disease.酿酒酵母菌血症:一种新出现的传染病。
Clin Infect Dis. 2005 Jun 1;40(11):1625-34. doi: 10.1086/429916. Epub 2005 Apr 25.

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