Tiedje D, Quer O, Breil B, Schrader A J, Bothe C, Kruse K, Bögemann M, Donner-Banzhoff N, Semjonow A
Prostatazentrum, Klinik für Urologie und Kinderurologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude A1, 48149, Münster, Deutschland.
Fachbereich Gesundheitswesen, Hochschule Niederrhein, Reinarzstr. 49, 47805, Krefeld, Deutschland.
Urologe A. 2017 Jul;56(7):910-916. doi: 10.1007/s00120-017-0352-1.
The German S3 guideline on prostate cancer gives recommendations on early detection of prostate cancer. In this study we analyzed the adherence of urologists in private practice from the administrative district of Münster, Germany to this guideline.
Data were collected through a semistructured survey of 22 urologists based on the COREQ checklist (Consolidated criteria for reporting qualitative research) in four focus groups consisting of five or six urologists in private practice. We developed 23 questions relating to 12 recommendations of the paragraphs of the S3 guidelines dealing with early detection of prostate cancer and prostate biopsy. The recommendations of the guideline are subdivided in nine "strong", one "optional recommendation" and two "statements". The adherence to the guideline was investigated by using frequency and qualitative content analysis (Mayring) based on a mixed methods design.
The urologists follow six of the nine "strong recommendations" of the guideline and deviate from three. Reasons for deviations from "strong recommendations" are the following: information about advantages and disadvantages of early detection for prostate cancer, recommendation of a prostate biopsy in case of PSA level ≥4 ng/ml, and indication for repeat biopsy.
Most of the "strong recommendations" are followed by the interviewed urologists of the administrative district of Münster. Contextually relevant deviations from "strong recommendations" are justified, e. g., the only limited transferability of the PSA threshold of 4 ng/ml derived from population-based studies of asymptomatic men to men presenting in a urologist's office.
德国前列腺癌S3指南给出了前列腺癌早期检测的建议。在本研究中,我们分析了德国明斯特行政区私人执业泌尿科医生对该指南的遵循情况。
基于COREQ清单(定性研究报告的综合标准),通过对22名泌尿科医生进行半结构化调查来收集数据,调查在由五或六名私人执业泌尿科医生组成的四个焦点小组中进行。我们针对S3指南中有关前列腺癌早期检测和前列腺活检的段落中的12条建议,设计了23个问题。该指南的建议分为九条“强烈建议”、一条“可选建议”和两条“声明”。基于混合方法设计,通过频率和定性内容分析(迈林法)来研究对该指南的遵循情况。
泌尿科医生遵循了该指南九条“强烈建议”中的六条,未遵循三条。未遵循“强烈建议”的原因如下:关于前列腺癌早期检测利弊的信息、PSA水平≥4 ng/ml时前列腺活检的建议以及重复活检的指征。
明斯特行政区接受访谈的泌尿科医生大多遵循“强烈建议”。与具体情况相关的对“强烈建议”的偏离是合理的,例如,基于无症状男性的人群研究得出的4 ng/ml的PSA阈值,对于在泌尿科就诊的男性而言,其可转移性有限。