Terry R M, Lewis F A, Griffiths S, Wells M, Bird C C
Department of ENT Surgery, Bradford Royal Infirmary, U.K.
J Pathol. 1987 Nov;153(3):245-8. doi: 10.1002/path.1711530308.
A study is reported in which an in situ hybridization technique for the demonstration of human papillomavirus (HPV) employing a biotin--streptavidin polyalkaline phosphatase complex has been successfully applied to formalin-fixed paraffin-processed tissue obtained from ten patients with juvenile laryngeal papillomatosis. In all cases, positive results were obtained for either HPV type 6 or 11. Normal vocal cord epithelium was negative.
